Transcription and splicing regulation by NLRC5 shape the interferon response in human pancreatic β cells
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DOI: 10.1126/sciadv.abn5732
Abstract: IFNα is a key regulator of the dialogue between pancreatic β cells and the immune system in early type 1 diabetes (T1D). IFNα up-regulates HLA class I expression in human β cells, fostering autoantigen presentation… read more here.
Keywords: hla class; regulation nlrc5; pancreatic cells; nlrc5 shape ... See more keywords
Transcription and splicing dynamics during early Drosophila development.
Sign Up to like & getrecommendations! Published in 2021 at "RNA"
DOI: 10.1261/rna.078933.121
Abstract: Widespread co-transcriptional splicing has been demonstrated from yeast to human. However, most studies to date addressing the kinetics of splicing relative to transcription used either Saccharomyces cerevisiae or metazoan cultured cell lines. Here, we adapted… read more here.
Keywords: transcription; transcription splicing; dynamics early; early drosophila ... See more keywords