Tuning the sequence specificity of a transcription terminator
Sign Up to like & getrecommendations! Published in 2019 at "Current Genetics"
DOI: 10.1007/s00294-019-00939-1
Abstract: The bacterial hexameric helicase known as Rho is an archetypal sequence-specific transcription terminator that typically halts the synthesis of a defined set of transcripts, particularly those bearing cytosine-rich 3′-untranslated regions. However, under conditions of translational… read more here.
Keywords: tuning sequence; transcription; rho; transcription terminator ... See more keywords
The bacterial transcription terminator, Rho, functions as an RNA:DNA hybrid (RDH) helicase in vivo
Sign Up to like & getrecommendations! Published in 2025 at "Biochemical Journal"
DOI: 10.1042/bcj20253089
Abstract: Ribonuclease HI (rnhA) removes the deleterious RNA:DNA hybrids (RDHs) by cleaving its RNA component. The bacterial transcription terminator Rho is an RNA-dependent 5′ → 3′ helicase capable of unwinding RDH formed on a single-stranded RNA… read more here.
Keywords: rdh; helicase; transcription terminator; rho ... See more keywords