DDB1 binds histone reader BRWD3 to activate the transcriptional cascade in adipogenesis and promote onset of obesity.
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DOI: 10.1016/j.celrep.2021.109281
Abstract: Obesity has become a global pandemic. Identification of key factors in adipogenesis helps to tackle obesity and related metabolic diseases. Here, we show that DDB1 binds the histone reader BRWD3 to promote adipogenesis and diet-induced… read more here.
Keywords: ddb1; brwd3; transcriptional cascade; obesity ... See more keywords