Adiposity is associated with widespread transcriptional changes and downregulation of longevity pathways in aged skeletal muscle.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cachexia, sarcopenia and muscle"
DOI: 10.1002/jcsm.13255
Abstract: BACKGROUND Amongst healthy older people, a number of correlates of impaired skeletal muscle mass and function have been defined. Although the prevalence of obesity is increasing markedly in this age group, information is sparse about… read more here.
Keywords: longevity; muscle; obesity; transcriptional changes ... See more keywords
Transcriptional Changes in Bifidobacterium bifidum Involved in Synergistic Multispecies Biofilms.
Sign Up to like & getrecommendations! Published in 2021 at "Microbial ecology"
DOI: 10.1007/s00248-021-01904-7
Abstract: Bifidobacterium bifidum is part of the core microbiota of healthy infant guts where it may form biofilms on epithelial cells, mucosa, and food particles in the gut lumen. Little is known about transcriptional changes in… read more here.
Keywords: synergistic multispecies; bifidobacterium bifidum; multispecies biofilms; bifidum ... See more keywords
Multiscale Approach to Deciphering the Molecular Mechanisms Involved in the Direct and Intergenerational Effect of Ibuprofen on Mosquito Aedes aegypti.
Sign Up to like & getrecommendations! Published in 2018 at "Environmental science & technology"
DOI: 10.1021/acs.est.8b00988
Abstract: The anti-inflammatory ibuprofen is a ubiquitous surface water contaminant. However, the chronic impact of this pharmaceutical on aquatic invertebrate populations remains poorly understood. In model insect Aedes aegypti, we investigated the intergenerational consequences of parental… read more here.
Keywords: aedes aegypti; direct intergenerational; ibuprofen; multiscale approach ... See more keywords
Differences in transcriptional changes in psoriasis and psoriatic arthritis skin with immunoglobulin gene enrichment in psoriatic arthritis.
Sign Up to like & getrecommendations! Published in 2023 at "Rheumatology"
DOI: 10.1093/rheumatology/kead195
Abstract: OBJECTIVES ∼20% of people with psoriasis develop psoriatic arthritis (PsA). Although genetic, clinical, and environmental risk factors have been identified, it is not known why some people with psoriasis develop PsA. The skin disease is… read more here.
Keywords: transcriptional changes; skin; psoriatic arthritis; changes psoriasis ... See more keywords
Transcriptional changes when Myxococcus xanthus preys on Escherichia coli suggest myxobacterial predators are constitutively toxic but regulate their feeding
Sign Up to like & getrecommendations! Published in 2018 at "Microbial Genomics"
DOI: 10.1099/mgen.0.000152
Abstract: Predation is a fundamental ecological process, but within most microbial ecosystems the molecular mechanisms of predation remain poorly understood. We investigated transcriptome changes associated with the predation of Escherichia coli by the myxobacterium Myxococcus xanthus… read more here.
Keywords: changes myxococcus; escherichia coli; myxococcus xanthus; predator ... See more keywords
Transcriptional changes in the aphid species Myzus cerasi under different host and environmental conditions
Sign Up to like & getrecommendations! Published in 2019 at "Insect Molecular Biology"
DOI: 10.1111/imb.12631
Abstract: Aphids feature complex life cycles, which in the case of many agriculturally important species involve primary and secondary host plant species. Whilst host alternation between primary and secondary host can occur in the field depending… read more here.
Keywords: secondary host; aphid species; changes aphid; host ... See more keywords
Response to Comments on Transcriptional Changes in Cancer Cells Induced by Exposure to a Healing Method
Sign Up to like & getrecommendations! Published in 2018 at "Dose-Response"
DOI: 10.1177/1559325818807780
Abstract: We appreciate the thorough review of our article and take this opportunity to clarify the concerns raised by Dr Rodrigues. An important point that readers shall keep in mind is the exploratory nature of the… read more here.
Keywords: healing method; exposure; expression; transcriptional changes ... See more keywords
Rice nucleosome patterns undergo remodeling coincident with stress-induced gene expression
Sign Up to like & getrecommendations! Published in 2017 at "BMC Genomics"
DOI: 10.1186/s12864-017-4397-8
Abstract: BackgroundFormation of nucleosomes along eukaryotic DNA has an impact on transcription. Major transcriptional changes occur in response to low external phosphate (Pi) in plants, but the involvement of chromatin-level mechanisms in Pi starvation responses have… read more here.
Keywords: transcriptional changes; starvation; rice; nucleosome patterns ... See more keywords
Complex and dynamic transcriptional changes allow the helminth Fasciola gigantica to adjust to its intermediate snail and definitive mammalian hosts
Sign Up to like & getrecommendations! Published in 2019 at "BMC Genomics"
DOI: 10.1186/s12864-019-6103-5
Abstract: BackgroundThe tropical liver fluke, Fasciola gigantica causes fasciolosis, an important disease of humans and livestock. We characterized dynamic transcriptional changes associated with the development of the parasite in its two hosts, the snail intermediate host… read more here.
Keywords: fasciola; dynamic transcriptional; fasciola gigantica; snail ... See more keywords
Profiling DNA break sites and transcriptional changes in response to contextual fear learning
Sign Up to like & getrecommendations! Published in 2021 at "PLoS ONE"
DOI: 10.1371/journal.pone.0249691
Abstract: Neuronal activity generates DNA double-strand breaks (DSBs) at specific loci in vitro and this facilitates the rapid transcriptional induction of early response genes (ERGs). Physiological neuronal activity, including exposure of mice to learning behaviors, also… read more here.
Keywords: transcriptional changes; profiling dna; response; dna break ... See more keywords
Single-Cell RNA Sequencing Reveals Cellular and Transcriptional Changes Associated With Traumatic Brain Injury
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.861428
Abstract: Traumatic brain injury (TBI) is currently a substantial public health problem and one of the leading causes of morbidity and mortality worldwide. However, the cellular and transcriptional changes in TBI at single-cell level have not… read more here.
Keywords: cell; traumatic brain; tbi; cellular transcriptional ... See more keywords