Transcriptional circuits in B cell transformation
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DOI: 10.1097/moh.0000000000000352
Abstract: Purpose of review Loss of IKAROS in committed B cell precursors causes a block in differentiation while at the same time augments aberrant cellular properties, such as bone marrow stromal adhesion, self-renewal and resistance to… read more here.
Keywords: cell differentiation; circuits cell; differentiation; cell transformation ... See more keywords
FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Research"
DOI: 10.1158/0008-5472.can-22-0671
Abstract: This work identifies a novel promoter that drives aberrant FOXR2 expression and delineates FOXR2 as a pan-cancer oncogene that specifically activates ETS transcriptional circuits across human cancers. read more here.
Keywords: ets transcriptional; pan cancer; activates ets; transcriptional circuits ... See more keywords