Abstract 3552: Induction of store operated calcium entry (SOCE) suppresses glioblastoma growth by inhibiting the Hippo pathway transcriptional coactivators YAP/TAZ
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-3552
Abstract: Glioblastomas (GBM) are the most aggressive brain cancers without effective therapeutics. The Hippo pathway transcriptional coactivators YAP/TAZ were implicated as drivers in GBM progression and could be therapeutic targets. Here, we found in an unbiased… read more here.
Keywords: transcriptional coactivators; pathway transcriptional; hippo pathway; yap taz ... See more keywords
The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation
Sign Up to like & getrecommendations! Published in 2017 at "Diabetes"
DOI: 10.2337/db17-0237
Abstract: p300 (EP300) and CBP (CREBBP) are transcriptional coactivators with histone acetyltransferase activity. Various β-cell transcription factors can recruit p300/CBP, and thus the coactivators could be important for β-cell function and health in vivo. We hypothesized… read more here.
Keywords: cell; transcriptional coactivators; p300 cbp; proliferation ... See more keywords
Transcriptional Coactivators: Driving Force of Plant Immunity
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.823937
Abstract: Salicylic acid (SA) is a plant defense signal that mediates local and systemic immune responses against pathogen invasion. However, the underlying mechanism of SA-mediated defense is very complex due to the involvement of various positive… read more here.
Keywords: immune responses; plant immunity; defense; plant ... See more keywords