Transcriptional and epi-transcriptional dynamics of SARS-CoV-2 during cellular infection
Sign Up to like & getrecommendations! Published in 2021 at "Cell Reports"
DOI: 10.1016/j.celrep.2021.109108
Abstract: SARS-CoV-2 uses subgenomic (sg)RNA to produce viral proteins for replication and immune evasion. We applied long-read RNA and cDNA sequencing to in vitro human and primate infection models to study transcriptional dynamics. Transcription-regulating sequence (TRS)-dependent… read more here.
Keywords: sgrna; transcriptional dynamics; transcriptional epi; epi transcriptional ... See more keywords
Sensory Nerves Regulate Transcriptional Dynamics of Lymph Node Cells.
Sign Up to like & getrecommendations! Published in 2021 at "Trends in immunology"
DOI: 10.1016/j.it.2021.01.008
Abstract: The nervous system plays important roles in homeostasis and inflammatory responses in tissues. However, the regulation of lymph nodes (LN) by nerves remains largely unknown. Huang et al. demonstrate that LNs are innervated by unique… read more here.
Keywords: transcriptional dynamics; dynamics lymph; sensory nerves; nerves regulate ... See more keywords
Transcriptional dynamics of induced pluripotent stem cell differentiation into β cells reveals full endodermal commitment and homology with human islets.
Sign Up to like & getrecommendations! Published in 2020 at "Cytotherapy"
DOI: 10.1016/j.jcyt.2020.10.004
Abstract: BACKGROUND AIMS Induced pluripotent stem cells (iPSCs) have the capacity to generate β cells in vitro, but the differentiation is incomplete and generates a variable percentage of off-target cells. Single-cell RNA sequencing offers the possibility… read more here.
Keywords: transcriptional dynamics; differentiation; pluripotent stem; induced pluripotent ... See more keywords
Transcriptional dynamics of Zn-accumulation in developing kernels of maize reveals important Zn-uptake mechanisms.
Sign Up to like & getrecommendations! Published in 2020 at "Genomics"
DOI: 10.1016/j.ygeno.2020.06.009
Abstract: In the present study, transcriptom analysis of 10-days old baby kernels of two contrasting maize genotypes, namely VQL-2 (high kernel Zn accumulator) and CM-145 (low kernel Zn accumulator), under low- and optimum- soil Zn conditions… read more here.
Keywords: transcriptional dynamics; kernels maize; dynamics accumulation; accumulation developing ... See more keywords
Single-cell RNA-sequencing reveals transcriptional dynamics of estrogen-induced dysplasia in the ovarian surface epithelium
Sign Up to like & getrecommendations! Published in 2018 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1007788
Abstract: Estrogen therapy increases the risk of ovarian cancer and exogenous estradiol accelerates the onset of ovarian cancer in mouse models. Both in vivo and in vitro, ovarian surface epithelial (OSE) cells exposed to estradiol develop… read more here.
Keywords: single cell; transcriptional dynamics; cell rna; rna sequencing ... See more keywords
Transcriptional dynamics of delaminating neuroblasts in the mouse otic vesicle.
Sign Up to like & getrecommendations! Published in 2023 at "Cell reports"
DOI: 10.2139/ssrn.4119740
Abstract: An abundance of research has recently highlighted the susceptibility of cochleovestibular ganglion (CVG) neurons to noise damage and aging in the adult cochlea, resulting in hearing deficits. Furthering our understanding of the transcriptional cascades that… read more here.
Keywords: otic vesicle; dynamics delaminating; delaminating neuroblasts; transcriptional dynamics ... See more keywords
Transcriptional dynamics of maize leaves, pollens and ovules to gain insights into heat stress-related responses
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2023.1117136
Abstract: Heat stress (HS) is one of the alarming issues today due to global warming and is the foremost detrimental to crop production. Maize is one of the versatile crops grown over different agro-climatic conditions. However,… read more here.
Keywords: heat stress; dynamics maize; heat; transcriptional dynamics ... See more keywords
Unraveling the Transcriptional Dynamics of NASH Pathogenesis Affecting Atherosclerosis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158229
Abstract: The prevalence of non-alcoholic steatohepatitis (NASH) is rapidly increasing and associated with cardiovascular disease (CVD), the major cause of mortality in NASH patients. Although sharing common risk factors, the mechanisms by which NASH may directly… read more here.
Keywords: unraveling transcriptional; dynamics nash; development; atherosclerosis development ... See more keywords