Dynamic Transcriptional and Epigenetic Changes Drive Cellular Plasticity in the Liver
Sign Up to like & getrecommendations! Published in 2021 at "Hepatology"
DOI: 10.1002/hep.31704
Abstract: Following liver injury, a fraction of hepatocytes adopt features of biliary epithelial cells (BECs) in a process known as biliary reprogramming. The aim of this study was to elucidate the molecular events accompanying this dramatic… read more here.
Keywords: dynamic transcriptional; cellular plasticity; changes drive; epigenetic changes ... See more keywords
Transcriptional and Epigenetic Regulation of Cardiac Electrophysiology
Sign Up to like & getrecommendations! Published in 2019 at "Pediatric Cardiology"
DOI: 10.1007/s00246-019-02160-w
Abstract: Spatiotemporal gene expression during cardiac development is a highly regulated process. Activation of key signaling pathways involved in electrophysiological programming, such as Notch and Wnt signaling, occurs in early cardiovascular development and these pathways are… read more here.
Keywords: cardiac electrophysiology; transcriptional epigenetic; regulation cardiac; epigenetic regulation ... See more keywords
Transcriptional, epigenetic and microRNA regulation of growth plate.
Sign Up to like & getrecommendations! Published in 2020 at "Bone"
DOI: 10.1016/j.bone.2020.115434
Abstract: Endochondral ossification is a critical event in bone formation, particularly in long shaft bones. Many cellular differentiation processes work in concert to facilitate the generation of cartilage primordium to formation of trabecular structures, all of… read more here.
Keywords: epigenetic microrna; growth plate; regulation growth; microrna regulation ... See more keywords
Transcriptional and epigenetic control of germline competence and specification.
Sign Up to like & getrecommendations! Published in 2019 at "Current opinion in cell biology"
DOI: 10.1016/j.ceb.2019.05.006
Abstract: In mammals, germline specification is induced during early embryogenesis when competent cells respond to extrinsic signals and form primordial germ cells (PGCs), the precursors of the gametes. The fusion of the two types of gametes,… read more here.
Keywords: epigenetic control; germline competence; specification; transcriptional epigenetic ... See more keywords
Transcriptional and epigenetic control of brown and beige adipose cell fate and function
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Molecular Cell Biology"
DOI: 10.1038/nrm.2017.72
Abstract: | White adipocytes store excess energy in the form of triglycerides, whereas brown and beige adipocytes dissipate energy in the form of heat. This thermogenic function relies on the activation of brown and beige adipocyte-specific… read more here.
Keywords: brown beige; adipose cell; biology; cell fate ... See more keywords
Distinct patterns of transcriptional and epigenetic alterations characterize acute and chronic kidney injury
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-35943-x
Abstract: Acute kidney injury (AKI) and chronic kidney disease (CKD) are considered early and late phases of a pathologic continuum of interconnected disease states. Although changes in gene expression patterns have recently been elucidated for the… read more here.
Keywords: aki ckd; kidney injury; ckd; transcriptional epigenetic ... See more keywords
Reprogramming and remodeling: transcriptional and epigenetic regulation of salicylic acid-mediated plant defense.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of experimental botany"
DOI: 10.1093/jxb/eraa072
Abstract: As a plant hormone, salicylic acid (SA) plays essential roles in plant defense against biotrophic and hemibiotrophic pathogens. Significant progress has been made in understanding the SA biosynthesis pathways and SA-mediated defense signaling networks in… read more here.
Keywords: salicylic acid; plant; defense; transcriptional epigenetic ... See more keywords
Transcriptional and epigenetic adaptation of maize chromosomes in Oat-Maize addition lines
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky209
Abstract: Abstract By putting heterologous genomic regulatory systems into contact, chromosome addition lines derived from interspecific or intergeneric crosses allow the investigation of transcriptional regulation in new genomic environments. Here, we report the transcriptional and epigenetic… read more here.
Keywords: addition; maize chromosomes; transcriptional epigenetic; addition lines ... See more keywords
Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types
Sign Up to like & getrecommendations! Published in 2017 at "Genome Biology"
DOI: 10.1186/s13059-017-1156-8
Abstract: BackgroundA healthy immune system requires immune cells that adapt rapidly to environmental challenges. This phenotypic plasticity can be mediated by transcriptional and epigenetic variability.ResultsWe apply a novel analytical approach to measure and compare transcriptional and… read more here.
Keywords: epigenetic variability; genome wide; immune; variability ... See more keywords
Strategies for the acquisition of transcriptional and epigenetic information in single cells.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of thoracic disease"
DOI: 10.21037/jtd.2016.08.17
Abstract: As the basic unit of living organisms, each single cell has unique molecular signatures and functions. Our ability to uncover the transcriptional and epigenetic signature of single cells has been hampered by the lack of… read more here.
Keywords: single cell; transcriptional epigenetic; single cells; epigenetic information ... See more keywords
It’s What and When You Eat: An Overview of Transcriptional and Epigenetic Responses to Dietary Perturbations in Pancreatic Islets
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.842603
Abstract: Our ever-changing modern environment is a significant contributor to the increased prevalence of many chronic diseases, and particularly, type 2 diabetes mellitus (T2DM). Although the modern era has ushered in numerous changes to our daily… read more here.
Keywords: epigenetic responses; overview transcriptional; transcriptional epigenetic; responses dietary ... See more keywords