Articles with "transcriptional factor" as a keyword



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The transcriptional factor YB-1 positively regulates Hsc70 transcription in Crassostrea hongkongensis.

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Published in 2018 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2017.12.110

Abstract: A Y-box binding protein ChYB-1 was discovered as a ChHsc70 promoter-associated protein in Crassostrea hongkongensis by DNA-affinity purification and mass spectrometry analysis. The overexpression of ChYB-1 in heterologous HEK293T cells led to clear enhancement of… read more here.

Keywords: crassostrea hongkongensis; transcription; chyb; transcriptional factor ... See more keywords
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Tea Domain Transcriptional Factor 4 (TEAD4) mitigates TGF-β signaling and hepatocellular carcinoma progression independently of YAP.

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Published in 2023 at "Journal of molecular cell biology"

DOI: 10.1093/jmcb/mjad010

Abstract: Tea domain transcriptional factor 4 (TEAD4) plays a pivotal role in tissue development and homeostasis by interacting with YAP in response to Hippo signaling inactivation. TEAD4 and YAP can also cooperate with TGF-β-activated Smad proteins… read more here.

Keywords: transcriptional factor; domain transcriptional; tea domain; factor tead4 ... See more keywords
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A transcriptional factor B paralog functions as an activator to DNA damage-responsive expression in archaea

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Published in 2018 at "Nucleic Acids Research"

DOI: 10.1093/nar/gky302

Abstract: Previously it was shown that UV irradiation induces a strong upregulation of tfb3 coding for a paralog of the archaeal transcriptional factor B (TFB) in Sulfolobus solfataricus, a crenarchaea. To investigate the function of this… read more here.

Keywords: dna damage; transcriptional factor; damage responsive; damage ... See more keywords
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TAMC: A deep-learning approach to predict motif-centric transcriptional factor binding activity based on ATAC-seq profile

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Published in 2022 at "PLoS Computational Biology"

DOI: 10.1371/journal.pcbi.1009921

Abstract: Determining transcriptional factor binding sites (TFBSs) is critical for understanding the molecular mechanisms regulating gene expression in different biological conditions. Biological assays designed to directly mapping TFBSs require large sample size and intensive resources. As… read more here.

Keywords: seq data; transcriptional factor; atac seq; seq ... See more keywords
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Nucleotide diversity patterns at the DREB1 transcriptional factor gene in the genome donor species of wheat (Triticum aestivum L)

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Published in 2019 at "PLoS ONE"

DOI: 10.1371/journal.pone.0217081

Abstract: Bread wheat (AABBDD) originated from the diploid progenitor Triticum urartu (AA), a relative of Aegilops speltoides (BB), and Ae. tauschii (DD). The DREB1 transcriptional factor plays key regulatory role in low-temperature tolerance. The modern breeding… read more here.

Keywords: diversity; nucleotide diversity; genome donor; transcriptional factor ... See more keywords
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Transcriptional factor-Mediated Regulation of Active Component Biosynthesis in Medicinal Plants.

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Published in 2020 at "Current pharmaceutical biotechnology"

DOI: 10.2174/1389201021666200622121809

Abstract: BACKGROUND Plants produce thousands of chemically diverse secondary metabolites, many of which have valuable pharmaceutical properties. There is much interest in the synthesis of these pharmaceutically-valuable compounds, including the key enzymes and the transcription factors… read more here.

Keywords: mediated regulation; transcriptional factor; medicinal plants; transcription factors ... See more keywords
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Biophysical and Biochemical Characterization of the Binding of the MarR-like Transcriptional Regulator Saro_0803 to the nov1 Promotor and Its Inhibition by Resveratrol

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Published in 2023 at "Biomolecules"

DOI: 10.3390/biom13030541

Abstract: Saro_0803 is a transcriptional factor modulating the transcription of the stilbene-degrading enzyme gene nov1 in Novosphingobium aromaticivorans DSM 12444. Reportedly, Saro_0803 undergoes resveratrol-mediated dissociation from the nov1 promotor and distinguishes resveratrol from its precursors, p-coumaric… read more here.

Keywords: transcriptional factor; resveratrol; saro; saro 0803 ... See more keywords
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Nfatc1 Is a Functional Transcriptional Factor Mediating Nell-1-Induced Runx3 Upregulation in Chondrocytes

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Published in 2018 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms19010168

Abstract: Neural EGFL like 1 (Nell-1) is essential for chondrogenic differentiation, maturation, and regeneration. Our previous studies have demonstrated that Nell-1’s pro-chondrogenic activities are predominantly reliant upon runt-related transcription factor 3 (Runx3)-mediated Indian hedgehog (Ihh) signaling.… read more here.

Keywords: nfatc1 functional; functional transcriptional; transcriptional factor; factor mediating ... See more keywords
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Transcriptional factor III A promotes colorectal cancer progression by upregulating cystatin A

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Published in 2022 at "World Journal of Gastrointestinal Oncology"

DOI: 10.4251/wjgo.v14.i10.1918

Abstract: BACKGROUND Advanced colorectal cancer (CRC) generally has poor outcomes and high mortality rates. Clarifying the molecular mechanisms underlying CRC progression is necessary to develop new diagnostic and therapeutic strategies to improve CRC outcome and decrease… read more here.

Keywords: transcriptional factor; progression; gtf3a; expression ... See more keywords