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Published in 2020 at "Molecular Metabolism"
DOI: 10.1016/j.molmet.2020.01.019
Abstract: Background Organisms can be primed by metabolic exposures to continue expressing response genes even once the metabolite is no longer available, and can affect the speed and magnitude of responsive gene expression during subsequent exposures.…
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Keywords:
metabolic memory;
transcriptional memory;
memory;
metabolic transcriptional ... See more keywords
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Published in 2022 at "eLife"
DOI: 10.1101/2022.02.11.480054
Abstract: For some inducible genes, the rate and molecular mechanism of transcriptional activation depends on the prior experiences of the cell. This phenomenon, called epigenetic transcriptional memory, accelerates reactivation and requires both changes in chromatin structure…
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Keywords:
transcriptional memory;
rna polymerase;
rnapii;
memory ... See more keywords
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Published in 2021 at "Life Science Alliance"
DOI: 10.26508/lsa.202101080
Abstract: Glucocorticoids are stress hormones that elicit various cellular responses. These responses are typically reversible; however, in some instances, a previous exposure is “remembered” and influences the response to a subsequent hormone encounter. Glucocorticoids are stress…
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Keywords:
hormone;
transcriptional memory;
response;
glucocorticoid signaling ... See more keywords
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Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.977653
Abstract: For certain inducible genes, the rate and molecular mechanism of transcriptional activation depends on the prior experiences of the cell. This phenomenon, called epigenetic transcriptional memory, accelerates reactivation and requires both changes in chromatin structure…
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Keywords:
transcriptional memory;
epigenetic transcriptional;
rnapii;
establishment inheritance ... See more keywords
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Published in 2019 at "BMB Reports"
DOI: 10.5483/bmbrep.2019.52.2.257
Abstract: Cells must fine-tune their gene expression programs for optimal cellular activities in their natural growth conditions. Transcriptional memory, a unique transcriptional response, plays a pivotal role in faster reactivation of genes upon environmental changes, and…
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Keywords:
response;
regulation;
transcriptional memory;
memory ... See more keywords