Transcriptional Profiling of C. elegans Adult Cells and Tissues with Age.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0592-9_16
Abstract: Multicellular organisms are composed of distinct cells and tissues that coordinate highly orchestrated responses to environmental challenges, including those that arise with age. Since C. elegans is a premier model system used to study the… read more here.
Keywords: transcriptional profiling; age; cells tissues; profiling elegans ... See more keywords
Analysis of Transcriptional Profiling of Chamber-Specific Human Cardiac Myocytes Derived from Pluripotent Stem Cells.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1484-6_20
Abstract: Differentiation protocols to direct cell fate decision from pluripotent stem cells to cardiac myocytes normally achieve high purity and quality of cells. Nonetheless, the highly specialized anatomy of the heart enables the possibility that acquisition… read more here.
Keywords: cardiac myocytes; transcriptional profiling; pluripotent stem; chamber specific ... See more keywords
Transcriptional Profiling During Neural Conversion.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1601-7_12
Abstract: The processes that underlie neuronal conversion ultimately involve a reorganization of transcriptional networks to establish a neuronal cell fate. As such, transcriptional profiling is a key component toward understanding this process. In this chapter, we… read more here.
Keywords: profiling neural; transcriptional profiling; neural conversion; conversion ... See more keywords
Transcriptional Profiling Mycobacterium tuberculosis from Patient Sputa.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7638-6_11
Abstract: The emergence of drug resistance threatens to destroy tuberculosis control programs worldwide, with resistance to all first-line drugs and most second-line drugs detected. Drug tolerance (or phenotypic drug resistance) is also likely to be clinically… read more here.
Keywords: drug; tuberculosis; transcriptional profiling; mycobacterium tuberculosis ... See more keywords
Transcriptional profiling reveals protective mechanisms in brains of long-lived mice
Sign Up to like & getrecommendations! Published in 2017 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2016.12.016
Abstract: The brain plays a central role in organismal aging but is itself most sensitive to aging-related functional impairments and pathologies. Insights into processes underlying brain aging are the basis to positively impact brain health. Using… read more here.
Keywords: transcriptional profiling; profiling reveals; reveals protective; protective mechanisms ... See more keywords
Corrigendum to “Combined metabolic and transcriptional profiling identifies pentose phosphate pathway activation by HSP27 phosphorylation during cerebral ischemia” [Neuroscience 349 (2017) 1–16]
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2017.04.018
Abstract: CORRIGENDUM TO ‘‘COMBINED METABOLIC AND TRANSCRIPTIONAL PROFILING IDENTIFIES PENTOSE PHOSPHATE PATHWAY ACTIVATION BY HSP27 PHOSPHORYLATION DURING CEREBRAL ISCHEMIA” [NEUROSCIENCE 349 (2017) 1–16] TAICHIRO IMAHORI, a KOHKICHI HOSODA, * TOMOAKI NAKAI, a YUSUKE YAMAMOTO, a YASUHIRO… read more here.
Keywords: medicine; corrigendum combined; transcriptional profiling; combined metabolic ... See more keywords
Transcriptional profiling of circulating tumor cells in multiple myeloma: a new model to understand disease dissemination
Sign Up to like & getrecommendations! Published in 2019 at "Leukemia"
DOI: 10.1038/s41375-019-0588-4
Abstract: The reason why a few myeloma cells egress from the bone marrow (BM) into peripheral blood (PB) remains unknown. Here, we investigated molecular hallmarks of circulating tumor cells (CTCs) to identify the events leading to… read more here.
Keywords: transcriptional profiling; tumor cells; circulating tumor; cells multiple ... See more keywords
Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation
Sign Up to like & getrecommendations! Published in 2020 at "Nature immunology"
DOI: 10.1038/s41590-020-0654-0
Abstract: Oxidative stress is a central part of innate immune-induced neurodegeneration. However, the transcriptomic landscape of central nervous system (CNS) innate immune cells contributing to oxidative stress is unknown, and therapies to target their neurotoxic functions… read more here.
Keywords: innate immune; stress; transcriptional profiling; oxidative stress ... See more keywords
Transcriptional Profiling of Somatostatin Interneurons in the Spinal Dorsal Horn
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-25110-7
Abstract: The spinal dorsal horn (SDH) is comprised of distinct neuronal populations that process different somatosensory modalities. Somatostatin (SST)-expressing interneurons in the SDH have been implicated specifically in mediating mechanical pain. Identifying the transcriptomic profile of… read more here.
Keywords: transcriptional profiling; spinal dorsal; dorsal horn; somatostatin interneurons ... See more keywords
Transcriptional profiling of the ductus arteriosus: Comparison of rodent microarrays and human RNA sequencing.
Sign Up to like & getrecommendations! Published in 2018 at "Seminars in perinatology"
DOI: 10.1053/j.semperi.2018.05.003
Abstract: DA closure is crucial for the transition from fetal to neonatal life. This closure is supported by changes to the DA's signaling and structural properties that distinguish it from neighboring vessels. Examining transcriptional differences between… read more here.
Keywords: arteriosus comparison; transcriptional profiling; rodent; profiling ductus ... See more keywords
Transcriptional profiling of MED Bemisia tabaci exposed to thermal stress and verification of HSP70 expression
Sign Up to like & getrecommendations! Published in 2021 at "Entomological Research"
DOI: 10.1111/1748-5967.12503
Abstract: Temperature changes impact agricultural production and also influence the behavior and community structure of many insect species. Bemisia tabaci, is an invasive and destructive pest with at least 44 cryptic species and occurring in over… read more here.
Keywords: thermal stress; transcriptional profiling; stress; bemisia tabaci ... See more keywords