Transcriptional Profiling of C. elegans Adult Cells and Tissues with Age.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0592-9_16
Abstract: Multicellular organisms are composed of distinct cells and tissues that coordinate highly orchestrated responses to environmental challenges, including those that arise with age. Since C. elegans is a premier model system used to study the… read more here.
Keywords: transcriptional profiling; age; cells tissues; profiling elegans ... See more keywords
Analysis of Transcriptional Profiling of Chamber-Specific Human Cardiac Myocytes Derived from Pluripotent Stem Cells.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1484-6_20
Abstract: Differentiation protocols to direct cell fate decision from pluripotent stem cells to cardiac myocytes normally achieve high purity and quality of cells. Nonetheless, the highly specialized anatomy of the heart enables the possibility that acquisition… read more here.
Keywords: cardiac myocytes; transcriptional profiling; pluripotent stem; chamber specific ... See more keywords
Transcriptional Profiling During Neural Conversion.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1601-7_12
Abstract: The processes that underlie neuronal conversion ultimately involve a reorganization of transcriptional networks to establish a neuronal cell fate. As such, transcriptional profiling is a key component toward understanding this process. In this chapter, we… read more here.
Keywords: profiling neural; transcriptional profiling; neural conversion; conversion ... See more keywords
Transcriptional Profiling Mycobacterium tuberculosis from Patient Sputa.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7638-6_11
Abstract: The emergence of drug resistance threatens to destroy tuberculosis control programs worldwide, with resistance to all first-line drugs and most second-line drugs detected. Drug tolerance (or phenotypic drug resistance) is also likely to be clinically… read more here.
Keywords: drug; tuberculosis; transcriptional profiling; mycobacterium tuberculosis ... See more keywords
Transcriptional profiling reveals protective mechanisms in brains of long-lived mice
Sign Up to like & getrecommendations! Published in 2017 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2016.12.016
Abstract: The brain plays a central role in organismal aging but is itself most sensitive to aging-related functional impairments and pathologies. Insights into processes underlying brain aging are the basis to positively impact brain health. Using… read more here.
Keywords: transcriptional profiling; profiling reveals; reveals protective; protective mechanisms ... See more keywords
Corrigendum to “Combined metabolic and transcriptional profiling identifies pentose phosphate pathway activation by HSP27 phosphorylation during cerebral ischemia” [Neuroscience 349 (2017) 1–16]
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2017.04.018
Abstract: CORRIGENDUM TO ‘‘COMBINED METABOLIC AND TRANSCRIPTIONAL PROFILING IDENTIFIES PENTOSE PHOSPHATE PATHWAY ACTIVATION BY HSP27 PHOSPHORYLATION DURING CEREBRAL ISCHEMIA” [NEUROSCIENCE 349 (2017) 1–16] TAICHIRO IMAHORI, a KOHKICHI HOSODA, * TOMOAKI NAKAI, a YUSUKE YAMAMOTO, a YASUHIRO… read more here.
Keywords: medicine; corrigendum combined; transcriptional profiling; combined metabolic ... See more keywords
Transcriptional profiling of circulating tumor cells in multiple myeloma: a new model to understand disease dissemination
Sign Up to like & getrecommendations! Published in 2019 at "Leukemia"
DOI: 10.1038/s41375-019-0588-4
Abstract: The reason why a few myeloma cells egress from the bone marrow (BM) into peripheral blood (PB) remains unknown. Here, we investigated molecular hallmarks of circulating tumor cells (CTCs) to identify the events leading to… read more here.
Keywords: transcriptional profiling; tumor cells; circulating tumor; cells multiple ... See more keywords
Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation
Sign Up to like & getrecommendations! Published in 2020 at "Nature immunology"
DOI: 10.1038/s41590-020-0654-0
Abstract: Oxidative stress is a central part of innate immune-induced neurodegeneration. However, the transcriptomic landscape of central nervous system (CNS) innate immune cells contributing to oxidative stress is unknown, and therapies to target their neurotoxic functions… read more here.
Keywords: innate immune; stress; transcriptional profiling; oxidative stress ... See more keywords
Time-dependent RNA transcriptional profiling of abomasal mucosa in cattle infected with Ostertagia ostertagi
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Data"
DOI: 10.1038/s41597-025-04640-6
Abstract: In this study, we infected Holstein calves with Ostertagia ostertagi stage 3 larvae (L3) and determined gene expression profiles of abomasal fundic and pyloric mucosa by RNA sequencing (RNA-seq) at 3–5, 7–9, 10, and 21… read more here.
Keywords: time dependent; time; ostertagia ostertagi; transcriptional profiling ... See more keywords
Transcriptional Profiling of Somatostatin Interneurons in the Spinal Dorsal Horn
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-25110-7
Abstract: The spinal dorsal horn (SDH) is comprised of distinct neuronal populations that process different somatosensory modalities. Somatostatin (SST)-expressing interneurons in the SDH have been implicated specifically in mediating mechanical pain. Identifying the transcriptomic profile of… read more here.
Keywords: transcriptional profiling; spinal dorsal; dorsal horn; somatostatin interneurons ... See more keywords
Transcriptional profiling in microglia across physiological and pathological states identifies a transcriptional module associated with neurodegeneration
Sign Up to like & getrecommendations! Published in 2024 at "Communications Biology"
DOI: 10.1038/s42003-024-06684-7
Abstract: Microglia are the resident immune cells of the central nervous system and are involved in brain development, homeostasis, and disease. New imaging and genomics technologies are revealing microglial complexity across developmental and functional states, brain… read more here.
Keywords: disease; microglia across; across physiological; physiological pathological ... See more keywords