The transcriptional regulator Zfat is essential for maintenance and differentiation of the adipocytes
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29890
Abstract: Adipocytes play crucial roles in the control of whole‐body energy homeostasis. Differentiation and functions of the adipocytes are regulated by various transcription factors. Zfat (zinc‐finger protein with AT‐hook) is a transcriptional regulator that controls messenger… read more here.
Keywords: transcriptional regulator; maintenance differentiation; differentiation; zfat ... See more keywords
SutA is a Global Transcriptional Regulator Operating during Slow Growth in Pseudomonas Aeruginosa
Sign Up to like & getrecommendations! Published in 2017 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.23840
Abstract: Chronic Pseudomonas aeruginosa infections, a major cause of morbidity and mortality for CF patients, are highly resistant to antibiotic treatment, and many lines of evidence suggest that this is due in part to slow-growing states… read more here.
Keywords: slow growth; global transcriptional; pseudomonas aeruginosa; suta global ... See more keywords
Biosensor-assisted transcriptional regulator engineering for Methylobacterium extorquens AM1 to improve mevalonate synthesis by increasing the acetyl-CoA supply.
Sign Up to like & getrecommendations! Published in 2017 at "Metabolic engineering"
DOI: 10.1016/j.ymben.2016.11.010
Abstract: Acetyl-CoA is not only an important intermediate metabolite for cells but also a significant precursor for production of industrially interesting metabolites. Methylobacterium extorquens AM1, a model strain of methylotrophic cell factories using methanol as carbon… read more here.
Keywords: mevalonate; transcriptional regulator; coa; extorquens am1 ... See more keywords
Transcriptional regulator CTR9 promotes hepatocellular carcinoma progression and metastasis via increasing PEG10 transcriptional activity.
Sign Up to like & getrecommendations! Published in 2021 at "Acta pharmacologica Sinica"
DOI: 10.1038/s41401-021-00812-3
Abstract: Cln Three Requiring 9 (CTR9), a scaffold protein of the polymerase-associated factor-1 (PAF1) complex (PAF1c), is primarily localized in the nucleus of cells. Recent studies show that CTR9 plays essential roles in the development of… read more here.
Keywords: ctr9; xenograft mouse; hepatocellular carcinoma; transcriptional regulator ... See more keywords
The transcriptional regulator HDP1 controls expansion of the inner membrane complex during early sexual differentiation of malaria parasites.
Sign Up to like & getrecommendations! Published in 2022 at "Nature microbiology"
DOI: 10.1038/s41564-021-01045-0
Abstract: Transmission of Plasmodium falciparum and other malaria parasites requires their differentiation from asexual blood stages into gametocytes, the non-replicative sexual stage necessary to infect the mosquito vector. This transition involves changes in gene expression and… read more here.
Keywords: hdp1; early sexual; malaria parasites; malaria ... See more keywords
Structural basis for HOCl recognition and regulation mechanisms of HypT, a hypochlorite-specific transcriptional regulator
Sign Up to like & getrecommendations! Published in 2019 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1811509116
Abstract: Significance Hypochlorous acid (HOCl) is a powerful oxidant that kills microorganisms. HypT has been identified as a HOCl-sensing transcription factor regulating several genes to enhance survival during HOCl stress in Escherichia coli. However, the structure… read more here.
Keywords: mechanism; hypt; transcriptional regulator; hocl ... See more keywords
Identification of differential microRNAs and messenger RNAs resulting from ASXL transcriptional regulator 3 knockdown during during heart development
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2062525
Abstract: ABSTRACT Congenital heart disease (CHD) is the most common birth defect. Although ASXL transcriptional regulator 3 (ASXL3) has been reported to cause hereditary CHD, ASXL3-mediated mechanisms in heart development remain unclear. In this study, we… read more here.
Keywords: heart development; asxl transcriptional; heart; asxl3 knockdown ... See more keywords
ZBTB24 is a transcriptional regulator that coordinates with DNMT3B to control DNA methylation
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky682
Abstract: Abstract The interplay between transcription factors and epigenetic writers like the DNA methyltransferases (DNMTs), and the role of this interplay in gene expression, is being increasingly appreciated. ZBTB24, a poorly characterized zinc-finger protein, or the… read more here.
Keywords: methylation; dnmt3b; dna; transcriptional regulator ... See more keywords
OhrR is a central transcriptional regulator of virulence in Dickeya zeae.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular plant pathology"
DOI: 10.1111/mpp.13141
Abstract: Dickeya zeae is the causal agent of rice foot rot disease. The pathogen is known to rely on a range of virulence factors, including phytotoxin zeamines, extracellular enzymes, cell motility, and biofilm, which collectively contribute… read more here.
Keywords: virulence; transcriptional regulator; regulator virulence; zeae ... See more keywords
The Novel Streptococcal Transcriptional Regulator XtgS Negatively Regulates Bacterial Virulence and Directly Represses PseP Transcription
Sign Up to like & getrecommendations! Published in 2020 at "Infection and Immunity"
DOI: 10.1128/iai.00035-20
Abstract: Streptococcus agalactiae (group B streptococcus [GBS]) has received continuous attention for its involvement in invasive infections and its broad host range. Transcriptional regulators have an important impact on bacterial adaptation to various environments. Research on… read more here.
Keywords: xtgs; transcription; gbs; transcriptional regulator ... See more keywords
Role of the LuxR family transcriptional regulator Lpg2524 in the survival of Legionella pneumophila in water.
Sign Up to like & getrecommendations! Published in 2017 at "Canadian journal of microbiology"
DOI: 10.1139/cjm-2016-0780
Abstract: The water-borne Gram-negative bacterium Legionella pneumophila (Lp) is the causative agent of Legionnaires' disease. Lp is typically transmitted to humans from water systems, where it grows inside amoebae. Survival of Lp in water is central… read more here.
Keywords: lpg2524; water; transcriptional regulator; legionella pneumophila ... See more keywords