Both the Infection Status and Inflammatory Microenvironment Induce Transcriptional Remodeling in Macrophages in Murine Leishmanial Lesions
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DOI: 10.1645/22-94
Abstract: Cutaneous leishmaniasis is caused by infection with the protozoan parasite Leishmania, which resides intracellularly in dermal macrophages (Mø), producing lesions. The skin lesions are characterized by proinflammatory cytokines and growth factors as well as inflammatory… read more here.
Keywords: microenvironment; infection; inflammatory microenvironment; transcriptional remodeling ... See more keywords
Transcriptional Remodeling Patterns in Murine Dendritic Cells Infected with Paracoccidioides brasiliensis: More Is Not Necessarily Better
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DOI: 10.3390/jof6040311
Abstract: Most people infected with the fungus Paracoccidioides spp. do not get sick, but approximately 5% develop paracoccidioidomycosis. Understanding how host immunity determinants influence disease development could lead to novel preventative or therapeutic strategies; hence, we… read more here.
Keywords: remodeling patterns; transcriptional remodeling; dendritic cells; strain ... See more keywords