Transcriptional repression shapes the identity and function of tissue macrophages.
Sign Up to like & getrecommendations! Published in 2021 at "FEBS open bio"
DOI: 10.1002/2211-5463.13269
Abstract: The changing extra- and intracellular microenvironment calls for rapid cell fate decisions that are precisely and primarily regulated at the transcriptional level. The cellular components of the immune system are excellent examples of how cells… read more here.
Keywords: tissue macrophages; tissue; function; identity ... See more keywords
Efficient Depletion of Fission Yeast Condensin by Combined Transcriptional Repression and Auxin-Induced Degradation.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9520-2_3
Abstract: Structural maintenance of chromosomes (SMC) complexes play pivotal roles in controlling chromatin organization. Condensin is an essential SMC complex that compacts chromatin to form condensed chromosomes in mitosis. Complete condensin inactivation is necessary to reveal… read more here.
Keywords: repression auxin; condensin; depletion; fission yeast ... See more keywords
The chromatin remodeler RSF1 coordinates epigenetic marks for transcriptional repression and DSB repair
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkab1093
Abstract: Abstract DNA lesions impact on local transcription and the damage-induced transcriptional repression facilitates efficient DNA repair. However, how chromatin dynamics cooperates with these two events remained largely unknown. We here show that histone H2A acetylation… read more here.
Keywords: transcriptional repression; dna; h2a; repair ... See more keywords
Modeling single-cell phenotypes links yeast stress acclimation to transcriptional repression and pre-stress cellular states
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.1101/2021.09.08.459442
Abstract: Stress defense and cell growth are inversely related in bulk culture analyses; however, these studies miss substantial cell-to-cell heterogeneity, thus obscuring true phenotypic relationships. Here, we devised a microfluidics system to characterize multiple phenotypes in… read more here.
Keywords: stress; cell; growth; msn2 ... See more keywords
Multi-omics analyses demonstrate a critical role for EHMT1 methyltransferase in transcriptional repression during oogenesis
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DOI: 10.1101/gr.277046.122
Abstract: GLP (EHMT1) is a multifunctional protein, best known for its role as an H3K9me1 and H3K9me2 methyltransferase through its reportedly obligatory dimerization with G9A (EHMT2). Here, we investigate the role of GLP in the oocyte… read more here.
Keywords: glp; g9a; glp cdko; cko ... See more keywords
RAMOSA1 ENHANCER LOCUS2-Mediated Transcriptional Repression Regulates Vegetative and Reproductive Architecture1[OPEN]
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DOI: 10.1104/pp.18.00913
Abstract: Genetic and molecular analysis of the maize REL2 transcriptional corepressor defines a function for the WD40 domain of TOPLESS proteins and reveals a major role for REL2 in meristem development. Transcriptional repression in multicellular organisms… read more here.
Keywords: vegetative reproductive; enhancer locus2; repression; ramosa1 enhancer ... See more keywords
Histone Deacetylases SRT1 and SRT2 Interact with ENAP1 to Mediate Ethylene-Induced Transcriptional Repression[OPEN]
Sign Up to like & getrecommendations! Published in 2018 at "Plant Cell"
DOI: 10.1105/tpc.17.00671
Abstract: Histone deacetylases STR1 and SRT2 interact with ENAP1, mediating transcriptional repression by regulating the levels of H3K9Ac in the ethylene response. Ethylene plays pleiotropic roles in plant growth, plant development, and stress responses. Although the… read more here.
Keywords: ethylene; srt1 srt2; histone deacetylases; srt2 interact ... See more keywords
Transcriptional Repression of MFG-E8 Causes Disturbance in the Homeostasis of Cell Cycle Through DOCK/ZP4/STAT Signaling in Buffalo Mammary Epithelial Cells
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.568660
Abstract: The mammary gland is a unique apocrine gland made up of a branching network of ducts that end in alveoli. It is an ideal system to study the molecular mechanisms associated with cell proliferation, differentiation,… read more here.
Keywords: epithelial cells; mammary epithelial; repression mfg; mfg ... See more keywords