The redox-sensing transcriptional repressor Rex is important for regulating the products distribution in Thermoanaerobacterium aotearoense SCUT27
Sign Up to like & getrecommendations! Published in 2020 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-020-10554-7
Abstract: The redox-sensing transcriptional repressor Rex (Rex) displayed diverse functions in different microbial species. Nowadays, only part function of rex has been verified in vitro and alcohol dehydrogenase gene (adhE) as the target of Rex has… read more here.
Keywords: transcriptional repressor; redox sensing; rex; sensing transcriptional ... See more keywords
Analysis of mouse male germ cell-specific or -predominant Tex13 family genes encoding proteins with transcriptional repressor activity
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Biology Reports"
DOI: 10.1007/s11033-021-06265-5
Abstract: Mammalian spermatogenesis is a highly organized process with successive mitotic, meiotic, and postmeiotic phases. This unique developmental process is characterized by the involvement of spermatogenic cell-specific genes. In this study, we identified and investigated testis… read more here.
Keywords: repressor activity; transcriptional repressor; male germ; activity ... See more keywords
Crystal structures of manganese-dependent transcriptional repressor MntR (Rv2788) from Mycobacterium tuberculosis in apo and manganese bound forms.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.05.005
Abstract: The pathogenic Mycobacterium tuberculosis encodes two members of the DtxR family metalloregulators, IdeR and MntR. IdeR represses gene expression in response to ferrous iron, while MntR (Rv2788) functions as a manganese-dependent transcriptional repressor, which represses… read more here.
Keywords: mntr rv2788; manganese dependent; transcriptional repressor; dependent transcriptional ... See more keywords
Transcriptional co-repressor CtBP2 orchestrates epithelial-mesenchymal transition through a novel transcriptional holocomplex with OCT1.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.12.070
Abstract: The epithelial to mesenchymal transition (EMT) is a cell intrinsic program controlling cellular morphological and phenotypic remodeling in a wide range of biological processes. Despite the accumulating evidence, the transcriptional networks regulating EMT still remain… read more here.
Keywords: novel transcriptional; mesenchymal transition; transcriptional repressor; repressor ... See more keywords
NF-κB c-Rel Dictates the Inflammatory Threshold by Acting as a Transcriptional Repressor
Sign Up to like & getrecommendations! Published in 2020 at "iScience"
DOI: 10.1016/j.isci.2020.100876
Abstract: Summary NF-κB/Rel family of transcription factors plays a central role in initiation and resolution of inflammatory responses. Here, we identified a function of the NF-κB subunit c-Rel as a transcriptional repressor of inflammatory genes. Genetic… read more here.
Keywords: transcriptional repressor; repressor; inflammatory threshold; rel dictates ... See more keywords
Inhibition of the transcriptional repressor LexA: Withstanding drug resistance by inhibiting the bacterial mechanisms of adaptation to antimicrobials.
Sign Up to like & getrecommendations! Published in 2019 at "Life sciences"
DOI: 10.1016/j.lfs.2019.117116
Abstract: AIMS LexA protein is a transcriptional repressor which regulates the expression of more than 60 genes belonging to the SOS global regulatory network activated by damages to bacterial DNA. Considering its role in bacteria, LexA… read more here.
Keywords: transcriptional repressor; inhibition; lexa self; resistance ... See more keywords
Clinical significance and biological function of transcriptional repressor GATA binding 1 in gastric cancer: a study based on data mining, RT-qPCR, immunochemistry, and vitro experiment
Sign Up to like & getrecommendations! Published in 2020 at "Cell Cycle"
DOI: 10.1080/15384101.2020.1827499
Abstract: ABSTRACT Transcriptional repressor GATA binding 1 (TRPS1) is a newly discovered transcription factor, which has been reported in many tumors, except for gastric cancer (GC). In this study, we aimed to grope for clinical significance… read more here.
Keywords: transcriptional repressor; function; repressor gata; significance ... See more keywords
The yeast Mig1 transcriptional repressor is dephosphorylated by glucose-dependent and -independent mechanisms
Sign Up to like & getrecommendations! Published in 2017 at "FEMS Microbiology Letters"
DOI: 10.1093/femsle/fnx133
Abstract: A yeast Saccharomyces cerevisiae Snf1 kinase, an analog of mammalian AMPK, regulates glucose derepression of genes required for utilization of alternative carbon sources through the transcriptional repressor Mig1. It has been suggested that the Glc7-Reg1… read more here.
Keywords: transcriptional repressor; yeast mig1; mig1 transcriptional; glc7 reg1 ... See more keywords
The transcriptional co-repressor SEED DORMANCY 4-LIKE (AtSDR4L) promotes embryonic-to-vegetative transition in Arabidopsis thaliana.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of integrative plant biology"
DOI: 10.1111/jipb.13360
Abstract: Repression of embryonic traits during the seed-to-seedling phase transition requires the inactivation of master transcription factors associated with embryogenesis. How the timing of such inactivation is controlled is unclear. Here, we report on a novel… read more here.
Keywords: transcriptional repressor; atsdr4l; seed; transition ... See more keywords
Functional and structural characterization of AntR, an Sb(III) responsive transcriptional repressor
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Microbiology"
DOI: 10.1111/mmi.14721
Abstract: The ant operon of the antimony‐mining bacterium Comamonas testosterone JL40 confers resistance to Sb(III). The operon is transcriptionally regulated by the product of the first gene in the operon, antR. AntR is a member of… read more here.
Keywords: antr; iii; functional structural; transcriptional repressor ... See more keywords
PA3225 Is a Transcriptional Repressor of Antibiotic Resistance Mechanisms in Pseudomonas aeruginosa
Sign Up to like & getrecommendations! Published in 2017 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.02114-16
Abstract: ABSTRACT The tssABC1 locus is part of the Hcp secretion island I (HSI-I) type VI secretion system (T6SS) in Pseudomonas aeruginosa. Previous work implicated the tssC1 gene in P. aeruginosa biofilm-specific antibiotic resistance, and tssC1… read more here.
Keywords: pa3225 transcriptional; pseudomonas aeruginosa; transcriptional repressor; resistance ... See more keywords