Transcriptional Reprogramming of Distinct Peripheral Sensory Neuron Subtypes after Axonal Injury
Sign Up to like & getrecommendations! Published in 2020 at "Neuron"
DOI: 10.1016/j.neuron.2020.07.026
Abstract: Primary somatosensory neurons are specialized to transmit specific types of sensory information through differences in cell size, myelination, and the expression of distinct receptors and ion channels, which together define their transcriptional and functional identity.… read more here.
Keywords: peripheral sensory; reprogramming distinct; distinct peripheral; transcriptional reprogramming ... See more keywords
The zoospores of the thraustochytrid Aurantiochytrium limacinum: transcriptional reprogramming and lipid metabolism associated to their specific functions.
Sign Up to like & getrecommendations! Published in 2020 at "Environmental microbiology"
DOI: 10.1111/1462-2920.14978
Abstract: Aurantiochytrium limacinum (Thraustochytriaceae, class Labyrinthulomycetes) is a marine Stramenopile and a pioneering mangrove decomposer. Its life cycle involves a non-motile stage and zoospore production. We observed that the composition of the medium, the presence of… read more here.
Keywords: metabolism; aurantiochytrium limacinum; lipid metabolism; transcriptional reprogramming ... See more keywords
Epigenetic transcriptional reprogramming by WT1 mediates a repair response during podocyte injury
Sign Up to like & getrecommendations! Published in 2020 at "Science Advances"
DOI: 10.1126/sciadv.abb5460
Abstract: The Wilms tumor-1 transcription factor regulates a repair process, providing insights on the pathogenesis of kidney disease. In the context of human disease, the mechanisms whereby transcription factors reprogram gene expression in reparative responses to… read more here.
Keywords: disease; wt1; podocyte injury; transcriptional reprogramming ... See more keywords
Transcriptional reprogramming of infiltrating neutrophils drives lung pathology in severe COVID-19 despite low viral load
Sign Up to like & getrecommendations! Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2022008834
Abstract: Troubling disparities in COVID-19-associated mortality emerged early, with nearly 70% of deaths confined to Black/African American (AA) patients in some areas. Nevertheless, targeted studies within this vulnerable population are scant. Here, we applied multi-omics single-cell… read more here.
Keywords: reprogramming infiltrating; despite low; viral load; pathology ... See more keywords
Transcriptional reprogramming in yeast using dCas9 and combinatorial gRNA strategies
Sign Up to like & getrecommendations! Published in 2017 at "Microbial Cell Factories"
DOI: 10.1186/s12934-017-0664-2
Abstract: BackgroundTranscriptional reprogramming is a fundamental process of living cells in order to adapt to environmental and endogenous cues. In order to allow flexible and timely control over gene expression without the interference of native gene… read more here.
Keywords: target; expression; yeast; transcriptional reprogramming ... See more keywords
New insights into transcriptional reprogramming during cellular stress
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DOI: 10.1242/jcs.238402
Abstract: ABSTRACT Cellular stress triggers reprogramming of transcription, which is required for the maintenance of homeostasis under adverse growth conditions. Stress-induced changes in transcription include induction of cyto-protective genes and repression of genes related to the… read more here.
Keywords: transcription; response; stress; cellular stress ... See more keywords
Sexual dimorphism of early transcriptional reprogramming in degenerating peripheral nerves
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.1029278
Abstract: Sexual dimorphism is a powerful yet understudied factor that influences the timing and efficiency of gene regulation in axonal injury and repair processes in the peripheral nervous system. Here, we identified common and distinct biological… read more here.
Keywords: early transcriptional; dimorphism early; transcriptional reprogramming; signaling pathways ... See more keywords
Chromatin-Based Transcriptional Reprogramming in Plants under Abiotic Stresses
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DOI: 10.3390/plants11111449
Abstract: Plants’ stress response machinery is characterized by an intricate network of signaling cascades that receive and transmit environmental cues and ultimately trigger transcriptional reprogramming. The family of epigenetic regulators that are the key players in… read more here.
Keywords: plants abiotic; abiotic stresses; chromatin based; transcriptional reprogramming ... See more keywords