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Published in 2020 at "Bioresource technology"
DOI: 10.1016/j.biortech.2020.123108
Abstract: The dynamic response mechanism of Candidatus Accumulibacter clades to environmental factors in enhanced biological phosphorus removal (EBPR) was unclear. This study investigated the relationship between the transcriptional responses of Candidatus Accumulibacter clades and environmental dynamics.…
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Keywords:
transcriptional responses;
candidatus accumulibacter;
clades environmental;
accumulibacter clades ... See more keywords
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Published in 2019 at "DNA repair"
DOI: 10.1016/j.dnarep.2019.05.002
Abstract: In response to the threat of DNA damage, cells exhibit a dramatic and multi-factorial response spanning from transcriptional changes to protein modifications, collectively known as the DNA damage response (DDR). Here, we review the literature…
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Keywords:
dna damage;
transcriptional responses;
responses dna;
damage ... See more keywords
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Published in 2022 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2022.113344
Abstract: Caenorhabditis elegans is a well-established model organism for toxicity testing of chemical substances. We recently demonstrated its potential for bioanalysis of the toxic potency of chemical contaminants in water. While many detoxification genes are homologues…
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Keywords:
differential expression;
expression;
expression genes;
transcriptional responses ... See more keywords
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Published in 2018 at "Ecological Indicators"
DOI: 10.1016/j.ecolind.2018.05.068
Abstract: Abstract Autophagy acts as important cytoprotective mechanism in response to adverse environment conditions. The hypothesis of the present study is that autophagy acts as protective responses to waterborne Zn exposure. To this end, the full-length…
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Keywords:
transcriptional responses;
exposure;
pelteobagrus fulvidraco;
responses waterborne ... See more keywords
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Published in 2019 at "Insect biochemistry and molecular biology"
DOI: 10.1016/j.ibmb.2019.103285
Abstract: Insecticides are a key tool in the management of many insect pests of agriculture, including soybean aphids. The selection imposed by insecticide use has often lead to the evolution of resistance by the target pest…
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Keywords:
transcriptional responses;
exposure;
soybean aphids;
aphids sublethal ... See more keywords
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Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-53457-1
Abstract: Understanding transcriptional responses to chemical perturbations is central to drug discovery, but exhaustive experimental screening of disease-compound combinations is unfeasible. To overcome this limitation, here we introduce PRnet, a perturbation-conditioned deep generative model that predicts…
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Keywords:
transcriptional responses;
drug discovery;
drug;
chemical perturbations ... See more keywords
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Published in 2025 at "Communications biology"
DOI: 10.1038/s42003-025-09226-x
Abstract: Cold stress poses significant challenges to livestock production; however, the regulatory mechanisms underlying porcine responses to chronic cold stress remain inadequately understood. To address this gap, we characterized the transcriptional responses of five metabolism-related tissues…
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Keywords:
transcriptional responses;
stress;
chronic cold;
stress induced ... See more keywords
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Published in 2022 at "Plant physiology"
DOI: 10.1093/plphys/kiac521
Abstract: To sustain growth when facing phosphate (Pi) starvation, plants trigger an array of adaptive responses that are largely controlled at transcriptional levels. In Arabidopsis (Arabidopsis thaliana), the four transcription factors of the PHOSPHATE RESPONSE 1…
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Keywords:
phl2 phl3;
phosphate response;
starvation;
phosphate starvation ... See more keywords
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Published in 2024 at "Plant Physiology"
DOI: 10.1093/plphys/kiae306
Abstract: In terrestrial ecosystems, plants act as primary producers by sequestering carbon from CO 2 and incorporating it into the soluble sugar form. These sugars are transported out of the leaves, usually in the form of…
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Keywords:
transcriptional responses;
trehalose trehalose;
direct indirect;
question direct ... See more keywords
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Published in 2020 at "Science Signaling"
DOI: 10.1126/scisignal.aba3244
Abstract: A disproportionately large response is induced by small increases in the abundance of a pathogen sensor. A small NOD to big changes NOD1 mediates proinflammatory and antimicrobial responses to pathogens. Infection with Helicobacter pylori, which…
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Keywords:
abundance;
transcriptional responses;
increase nod1;
nod1 abundance ... See more keywords
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Published in 2025 at "Acta Neuropathologica Communications"
DOI: 10.1186/s40478-025-02062-4
Abstract: Neonatal hypoxic-ischemic (H-I) brain injury, a leading cause of neurodevelopmental disabilities, severely affects the metabolically active and neurogenic hippocampus. To investigate its acute effects and identify drug targets for early therapeutic windows, we applied single-nucleus…
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Keywords:
hippocampus;
transcriptional responses;
cell;
vulnerability ... See more keywords