Articles with "transcriptional responses" as a keyword



Transcriptional responses of Candidatus Accumulibacter clades to environmental dynamics in enhanced biological phosphorus removal.

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Published in 2020 at "Bioresource technology"

DOI: 10.1016/j.biortech.2020.123108

Abstract: The dynamic response mechanism of Candidatus Accumulibacter clades to environmental factors in enhanced biological phosphorus removal (EBPR) was unclear. This study investigated the relationship between the transcriptional responses of Candidatus Accumulibacter clades and environmental dynamics.… read more here.

Keywords: transcriptional responses; candidatus accumulibacter; clades environmental; accumulibacter clades ... See more keywords
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Transcriptional responses to DNA damage.

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Published in 2019 at "DNA repair"

DOI: 10.1016/j.dnarep.2019.05.002

Abstract: In response to the threat of DNA damage, cells exhibit a dramatic and multi-factorial response spanning from transcriptional changes to protein modifications, collectively known as the DNA damage response (DDR). Here, we review the literature… read more here.

Keywords: dna damage; transcriptional responses; responses dna; damage ... See more keywords

Differential expression of genes in C. elegans reveals transcriptional responses to indirect-acting xenobiotic compounds and insensitivity to 2,3,7,8-tetrachlorodibenzodioxin.

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Published in 2022 at "Ecotoxicology and environmental safety"

DOI: 10.1016/j.ecoenv.2022.113344

Abstract: Caenorhabditis elegans is a well-established model organism for toxicity testing of chemical substances. We recently demonstrated its potential for bioanalysis of the toxic potency of chemical contaminants in water. While many detoxification genes are homologues… read more here.

Keywords: differential expression; expression; expression genes; transcriptional responses ... See more keywords

Characterization of twelve autophagy-related genes from yellow catfish Pelteobagrus fulvidraco and their transcriptional responses to waterborne zinc exposure

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Published in 2018 at "Ecological Indicators"

DOI: 10.1016/j.ecolind.2018.05.068

Abstract: Abstract Autophagy acts as important cytoprotective mechanism in response to adverse environment conditions. The hypothesis of the present study is that autophagy acts as protective responses to waterborne Zn exposure. To this end, the full-length… read more here.

Keywords: transcriptional responses; exposure; pelteobagrus fulvidraco; responses waterborne ... See more keywords
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Transcriptional responses of soybean aphids to sublethal insecticide exposure.

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Published in 2019 at "Insect biochemistry and molecular biology"

DOI: 10.1016/j.ibmb.2019.103285

Abstract: Insecticides are a key tool in the management of many insect pests of agriculture, including soybean aphids. The selection imposed by insecticide use has often lead to the evolution of resistance by the target pest… read more here.

Keywords: transcriptional responses; exposure; soybean aphids; aphids sublethal ... See more keywords

Predicting transcriptional responses to novel chemical perturbations using deep generative model for drug discovery

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Published in 2024 at "Nature Communications"

DOI: 10.1038/s41467-024-53457-1

Abstract: Understanding transcriptional responses to chemical perturbations is central to drug discovery, but exhaustive experimental screening of disease-compound combinations is unfeasible. To overcome this limitation, here we introduce PRnet, a perturbation-conditioned deep generative model that predicts… read more here.

Keywords: transcriptional responses; drug discovery; drug; chemical perturbations ... See more keywords

Chronic cold stress induced transcriptomic alterations in multi-metabolically active tissues of pigs.

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Published in 2025 at "Communications biology"

DOI: 10.1038/s42003-025-09226-x

Abstract: Cold stress poses significant challenges to livestock production; however, the regulatory mechanisms underlying porcine responses to chronic cold stress remain inadequately understood. To address this gap, we characterized the transcriptional responses of five metabolism-related tissues… read more here.

Keywords: transcriptional responses; stress; chronic cold; stress induced ... See more keywords

PHOSPHATE RESPONSE 1 family members act distinctly to regulate transcriptional responses to phosphate starvation.

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Published in 2022 at "Plant physiology"

DOI: 10.1093/plphys/kiac521

Abstract: To sustain growth when facing phosphate (Pi) starvation, plants trigger an array of adaptive responses that are largely controlled at transcriptional levels. In Arabidopsis (Arabidopsis thaliana), the four transcription factors of the PHOSPHATE RESPONSE 1… read more here.

Keywords: phl2 phl3; phosphate response; starvation; phosphate starvation ... See more keywords

Trehalose or not-trehalose: The question of direct vs. indirect transcriptional responses to the sugar trehalose-6-phosphate

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Published in 2024 at "Plant Physiology"

DOI: 10.1093/plphys/kiae306

Abstract: In terrestrial ecosystems, plants act as primary producers by sequestering carbon from CO 2 and incorporating it into the soluble sugar form. These sugars are transported out of the leaves, usually in the form of… read more here.

Keywords: transcriptional responses; trehalose trehalose; direct indirect; question direct ... See more keywords
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A small sustained increase in NOD1 abundance promotes ligand-independent inflammatory and oncogene transcriptional responses

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Published in 2020 at "Science Signaling"

DOI: 10.1126/scisignal.aba3244

Abstract: A disproportionately large response is induced by small increases in the abundance of a pathogen sensor. A small NOD to big changes NOD1 mediates proinflammatory and antimicrobial responses to pathogens. Infection with Helicobacter pylori, which… read more here.

Keywords: abundance; transcriptional responses; increase nod1; nod1 abundance ... See more keywords

Early transcriptional responses reveal cell type-specific vulnerability and neuroprotective mechanisms in the neonatal ischemic hippocampus

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Published in 2025 at "Acta Neuropathologica Communications"

DOI: 10.1186/s40478-025-02062-4

Abstract: Neonatal hypoxic-ischemic (H-I) brain injury, a leading cause of neurodevelopmental disabilities, severely affects the metabolically active and neurogenic hippocampus. To investigate its acute effects and identify drug targets for early therapeutic windows, we applied single-nucleus… read more here.

Keywords: hippocampus; transcriptional responses; cell; vulnerability ... See more keywords