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Published in 2022 at "Genetics"
DOI: 10.1093/genetics/iyac180
Abstract: Mating-type switching in the budding yeast Saccharomyces cerevisiae relies on the Sir protein complex to silence HML and HMR, the two loci containing copies of the alleles of the mating type locus, MAT. Sir-based transcriptional…
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Keywords:
locus;
hml;
transcriptional silencing;
gene ... See more keywords
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Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky387
Abstract: Abstract The bacterial histone-like protein H-NS silences AT-rich DNA, binding DNA as ‘stiffened’ filaments or ‘bridged’ intrastrand loops. The switch between these modes has been suggested to depend on the concentration of divalent cations, in…
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Keywords:
transcriptional silencing;
dna;
silencing;
silencing magnesium ... See more keywords
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Published in 2018 at "Molecular Microbiology"
DOI: 10.1111/mmi.13932
Abstract: Transcriptional silencing and anti‐silencing mechanisms modulate bacterial physiology and virulence in many human pathogens. In Shigella species, many virulence plasmid genes are silenced by the histone‐like nucleoid structuring protein H‐NS and anti‐silenced by the virulence…
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Keywords:
transcriptional silencing;
virulence;
anti silencing;
shigella ... See more keywords