Integrative spatial analysis of cell morphologies and transcriptional states with MUSE.
Sign Up to like & getrecommendations! Published in 2022 at "Nature biotechnology"
DOI: 10.1038/s41587-022-01251-z
Abstract: Spatial transcriptomics enables the simultaneous measurement of morphological features and transcriptional profiles of the same cells or regions in tissues. Here we present multi-modal structured embedding (MUSE), an approach to characterize cells and tissue regions… read more here.
Keywords: cell morphologies; integrative spatial; spatial analysis; transcriptional states ... See more keywords
Distinct stage-specific transcriptional states of B cells derived from human tonsillar tissue
Sign Up to like & getrecommendations! Published in 2023 at "JCI Insight"
DOI: 10.1172/jci.insight.155199
Abstract: B cells within secondary lymphoid tissues encompass a diversity of activation states and multiple maturation processes that reflect antigen recognition and transition through the germinal center (GC) reaction, in which mature B cells differentiate into… read more here.
Keywords: cell; states cells; stage specific; transcriptional states ... See more keywords