The proneural gene ASCL1 governs the transcriptional subgroup affiliation in glioblastoma stem cells by directly repressing the mesenchymal gene NDRG1
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DOI: 10.1038/s41418-018-0248-7
Abstract: Achaete-scute homolog 1 gene (ASCL1) is a gene classifier for the proneural (PN) transcriptional subgroup of glioblastoma (GBM) that has a relevant role in the neuronal-like differentiation of GBM cancer stem cells (CSCs) through the… read more here.
Keywords: gene ascl1; expression; ascl1; transcriptional subgroup ... See more keywords