Genome-wide identification of Wnt/β-catenin transcriptional targets during Xenopus gastrulation.
Sign Up to like & getrecommendations! Published in 2017 at "Developmental biology"
DOI: 10.1016/j.ydbio.2016.03.021
Abstract: The canonical Wnt/β-catenin signaling pathway plays multiple roles during Xenopus gastrulation, including posteriorization of the neural plate, patterning of the mesoderm, and induction of the neural crest. Wnt signaling stabilizes β-catenin, which then activates target… read more here.
Keywords: wnt; xenopus gastrulation; wnt catenin; transcriptional targets ... See more keywords
Mapping the chromatin landscape and Blimp1 transcriptional targets that regulate trophoblast differentiation
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-06859-9
Abstract: Trophoblast stem cells (TSCs) give rise to specialized cell types within the placenta. However, the regulatory mechanisms that guide trophoblast cell fate decisions during placenta development remain ill defined. Here we exploited ATAC-seq and transcriptional… read more here.
Keywords: chromatin; gene expression; chromatin landscape; landscape blimp1 ... See more keywords
Comprehensive multi-omics analysis uncovers a group of TGF-β-regulated genes among lncRNA EPR direct transcriptional targets
Sign Up to like & getrecommendations! Published in 2020 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkaa628
Abstract: Abstract Long non-coding RNAs (lncRNAs) can affect multiple layers of gene expression to control crucial cellular functions. We have previously demonstrated that the lncRNA EPR, by controlling gene expression at different levels, affects cell proliferation… read more here.
Keywords: direct transcriptional; analysis; group; gene ... See more keywords