ΔNp63-Senataxin circuit controls keratinocyte differentiation by promoting the transcriptional termination of epidermal genes
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DOI: 10.1073/pnas.2104718119
Abstract: Significance ΔNp63 is a master regulator of skin homeostasis since it finely controls keratinocyte differentiation and proliferation. Here, we provide cellular and molecular evidence demonstrating the functional role of a ΔNp63 interactor, the R-loop–resolving enzyme… read more here.
Keywords: np63 senataxin; controls keratinocyte; keratinocyte differentiation; transcriptional termination ... See more keywords