Stroke target identification guided by astrocyte transcriptome analysis
Sign Up to like & getrecommendations! Published in 2019 at "Glia"
DOI: 10.1002/glia.23544
Abstract: Astrocytes support normal brain function, but may also contribute to neurodegeneration when they become reactive under pathological conditions such as stroke. However, the molecular underpinnings of this context‐dependent interplay between beneficial and detrimental properties in… read more here.
Keywords: transcriptome analysis; identification guided; target identification; guided astrocyte ... See more keywords
Transcriptome analysis provides critical answers to the “variants of uncertain significance” conundrum
Sign Up to like & getrecommendations! Published in 2022 at "Human Mutation"
DOI: 10.1002/humu.24394
Abstract: While whole‐genome and exome sequencing have transformed our collective understanding of genetics' role in disease pathogenesis, there are certain conditions and populations for whom DNA‐level data fails to identify the underlying genetic etiology. Specifically, patients… read more here.
Keywords: transcriptome analysis; uncertain significance; analysis; provides critical ... See more keywords
Transcriptome Analysis Revealed Accumulation- Assimilation of Selenium and Physio-Biochemical Changes in Alfalfa (Medicago sativa L.) Leaves.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.11816
Abstract: BACKGROUND Selenium (Se) is an increasing concern for the investigators predominantly because of its consumption in the human body mainly from crops. As the fourth largest plant crop globally, alfalfa is one of the most… read more here.
Keywords: transcriptome analysis; assimilation; accumulation assimilation; selenium ... See more keywords
Single‐cell transcriptome analysis of fractional CO2 laser efficiency in treating a mouse model of alopecia
Sign Up to like & getrecommendations! Published in 2022 at "Lasers in Surgery and Medicine"
DOI: 10.1002/lsm.23590
Abstract: Hair loss, including alopecia, is a common dermatological issue worldwide. At present, the application of fractional carbon dioxide (CO2) laser in the treatment of alopecia has been documented; however, the results vary between reports. These… read more here.
Keywords: co2 laser; transcriptome analysis; cell transcriptome; laser ... See more keywords
Transcriptome analysis of zebrafish embryos exposed to deltamethrin
Sign Up to like & getrecommendations! Published in 2017 at "Environmental Toxicology"
DOI: 10.1002/tox.22376
Abstract: Deltamethrin (DTM), a type II pyrethroid, is one of the most commonly used insecticides. The increased use of pyrethroid leads to potential adverse effects, particularly in sensitive populations such as children and pregnant women. None… read more here.
Keywords: transcriptome analysis; embryos; zebrafish embryos; embryos exposed ... See more keywords
Transcriptome Analysis of PA Gain and Loss of Function Mutants.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7398-9_30
Abstract: Functional genomics has become a forefront methodology for plant science thanks to the widespread development of microarray technology. While technical difficulties associated with the process of obtaining raw expression data have been diminishing, allowing the… read more here.
Keywords: function mutants; transcriptome analysis; gain loss; methodology ... See more keywords
Transcriptome Analysis of Sclerotinia sclerotiorum at Different Infection Stages on Brassica napus
Sign Up to like & getrecommendations! Published in 2017 at "Current Microbiology"
DOI: 10.1007/s00284-017-1309-8
Abstract: Sclerotinia sclerotiorum is one of the most important plant pathogens, causing enormous losses in a variety of economically important crops including Brassica napus. The interaction of S. sclerotiorum with its hosts is more complex than… read more here.
Keywords: transcriptome analysis; sclerotinia sclerotiorum; infection; sclerotiorum ... See more keywords
Transcriptome analysis of Leucojum aestivum and identification of genes involved in norbelladine biosynthesis
Sign Up to like & getrecommendations! Published in 2022 at "Planta"
DOI: 10.1007/s00425-021-03741-x
Abstract: Main conclusion Transcriptome analysis of Leucojum aestivum led to the identification of 50 key genes associated with Amaryllidaceae alkaloid biosynthesis including norbelladine synthase which localized in the cytosol and catalyzed norbelladine formation. Abstract The Amaryllidaceae… read more here.
Keywords: biosynthesis; analysis; leucojum aestivum; transcriptome analysis ... See more keywords
Comparative transcriptome analysis reveals the regulation network for fiber strength in cotton.
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology letters"
DOI: 10.1007/s10529-022-03236-z
Abstract: OBJECTIVE Determine the effect of secondary cell wall (SCW) thickness and microcrystalline cellulose content (MCC) on mature fiber strength (FS) and reveal through comparative transcriptome analysis the molecular regulation network governing FS in cotton. RESULTS… read more here.
Keywords: analysis; comparative transcriptome; fiber strength; network ... See more keywords
Transcriptome Analysis of iPSC-Derived Neurons from Rubinstein-Taybi Patients Reveals Deficits in Neuronal Differentiation
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Neurobiology"
DOI: 10.1007/s12035-020-01983-6
Abstract: Rubinstein-Taybi syndrome (RSTS) is a rare multisystem developmental disorder with moderate to severe intellectual disability caused by heterozygous mutations of either CREBBP or EP300 genes encoding CBP/p300 chromatin regulators. We explored the gene programs and… read more here.
Keywords: transcriptome analysis; derived neurons; rubinstein taybi; differentiation ... See more keywords
Comparative de novo flower transcriptome analysis of polygamodioecious tree Garcinia indica
Sign Up to like & getrecommendations! Published in 2019 at "3 Biotech"
DOI: 10.1007/s13205-019-1601-3
Abstract: To extend our understanding of molecular mechanism of sex determination in agro-economically important, polygamodioecious tree Garcinia indica (Kokum), high-throughput, next-generation flower transcriptome sequencing (NGS), and comparative analyses were performed to investigate differentially expressed gene in… read more here.
Keywords: tree garcinia; transcriptome analysis; indica; flower transcriptome ... See more keywords