Genetic diversity and population structure of the medicinal plant Docynia delavayi (Franch.) Schneid revealed by transcriptome-based SSR markers
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Applied Research on Medicinal and Aromatic Plants"
DOI: 10.1016/j.jarmap.2021.100294
Abstract: Abstract Docynia delavayi is a wild fruit tree with high medicinal value that grows in southwest China. The exploitation and utilization of D. delavayi as a wild resource is constrained by a relative lack of… read more here.
Keywords: docynia delavayi; delavayi; genetic diversity; transcriptome based ... See more keywords
Transcriptome-Based Mining of the Strong Promoters for Hyperproduction of Gibberellin GA3 in Fusarium fujikuroi.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.5c00408
Abstract: Gibberellin GA3 is a plant growth regulator with significant applications in agriculture, and Fusarium fujikuroi has gained attention as an excellent host for the industrial production of GA3. Although numerous gene-editing tools have been developed,… read more here.
Keywords: fusarium fujikuroi; ga3; gibberellin ga3; transcriptome based ... See more keywords
TRIOMPHE: Transcriptome-Based Inference and Generation of Molecules with Desired Phenotypes by Machine Learning
Sign Up to like & getrecommendations! Published in 2021 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.1c00967
Abstract: One of the most challenging tasks in the drug-discovery process is the efficient identification of small molecules with desired phenotypes. In this study, we propose a novel computational method for omics-based de novo drug design,… read more here.
Keywords: desired phenotypes; based inference; transcriptome based; triomphe transcriptome ... See more keywords
Transcriptome-based molecular subtypes and differentiation hierarchies improve the classification framework of acute myeloid leukemia
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2211429119
Abstract: Significance Although the genetic intricacies of acute myeloid leukemia have been unmasked, the transcriptomic landscape remains incompletely defined and poorly translated into clinical practice. In this study, we evaluated the transcriptome repertoire in a large… read more here.
Keywords: myeloid leukemia; transcriptome based; classification; acute myeloid ... See more keywords
Transcriptome‐based target‐enrichment baits for stony corals (Cnidaria: Anthozoa: Scleractinia)
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Ecology Resources"
DOI: 10.1111/1755-0998.13150
Abstract: Despite the ecological and economic significance of stony corals (Scleractinia), a robust understanding of their phylogeny remains elusive due to patchy taxonomic and genetic sampling, as well as the limited availability of informative markers. To… read more here.
Keywords: loci; based target; stony corals; transcriptome based ... See more keywords
Transcriptome-based variant calling and aberrant mRNA discovery enhance diagnostic efficiency for neuromuscular diseases
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Genetics"
DOI: 10.1136/jmedgenet-2021-108307
Abstract: Background Whole-exome sequencing-based diagnosis of rare diseases typically yields 40%–50% of success rate. Precise diagnosis of the patients with neuromuscular disorders (NMDs) has been hampered by locus heterogeneity or phenotypic heterogeneity. We evaluated the utility… read more here.
Keywords: transcriptome based; aberrant splicing; rna seq; based variant ... See more keywords
expHRD: an individualized, transcriptome-based prediction model for homologous recombination deficiency assessment in cancer
Sign Up to like & getrecommendations! Published in 2024 at "BMC Bioinformatics"
DOI: 10.1186/s12859-024-05854-y
Abstract: Background Homologous recombination deficiency (HRD) stands as a clinical indicator for discerning responsive outcomes to platinum-based chemotherapy and poly ADP-ribose polymerase (PARP) inhibitors. One of the conventional approaches to HRD prognostication has generally centered on… read more here.
Keywords: cancer; recombination deficiency; transcriptome based; prediction ... See more keywords
Transcriptome-based approaches for clarification of nutritional responses and improvement of crop production
Sign Up to like & getrecommendations! Published in 2021 at "Breeding Science"
DOI: 10.1270/jsbbs.20098
Abstract: Genome-wide transcriptome profiling is a powerful tool for identifying key genes and pathways involved in plant development and physiological processes. This review summarizes studies that have used transcriptome profiling mainly in rice to focus on… read more here.
Keywords: nutritional responses; transcriptome based; based approaches; transcriptome ... See more keywords
A transcriptome-based classifier to determine molecular subtypes in medulloblastoma
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1008263
Abstract: Medulloblastoma is a highly heterogeneous pediatric brain tumor with five molecular subtypes, Sonic Hedgehog TP53-mutant, Sonic Hedgehog TP53-wildtype, WNT, Group 3, and Group 4, defined by the World Health Organization. The current mechanism for classification… read more here.
Keywords: medulloblastoma; group; transcriptome based; based classifier ... See more keywords
Identification of Chilling Accumulation-Associated Genes for Litchi Flowering by Transcriptome-Based Genome-Wide Association Studies
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.819188
Abstract: Litchi is an important Sapindaceae fruit tree. Flowering in litchi is triggered by low temperatures in autumn and winter. It can be divided into early-, medium-, and late-flowering phenotypes according to the time for floral… read more here.
Keywords: accumulation; transcriptome based; chilling accumulation; based genome ... See more keywords
Transcriptome-Based Spatiotemporal Analysis of Drought Response Mechanisms in Two Distinct Peanut Cultivars
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms252211895
Abstract: Drought tolerance varies among different peanut (Arachis hypogaea L.) cultivars. Here, drought responses of two cultivars, Huayu 22 (HY22) with drought tolerance and Fuhua 18 (FH18) with drought sensitivity, were compared at the morphological, physiological,… read more here.
Keywords: drought; peanut; analysis; response ... See more keywords