Iterative Single-Cell Analyses Define the Transcriptome of the First Functional Hematopoietic Stem Cells
Sign Up to like & getrecommendations! Published in 2020 at "Cell Reports"
DOI: 10.1016/j.celrep.2020.107627
Abstract: Summary Whereas hundreds of cells in the mouse embryonic aorta transdifferentiate to hematopoietic cells, only very few establish hematopoietic stem cell (HSC) identity at a single time point. The Gata2 transcription factor is essential for… read more here.
Keywords: single cell; hsc; transcriptome first; first functional ... See more keywords
1013 – CAPTURING THE TRANSCRIPTOME OF THE FIRST FUNCTIONAL HEMATOPOIETIC STEM CELLS
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Hematology"
DOI: 10.1016/j.exphem.2020.09.013
Abstract: Cell fate and behavior are regulated by dynamic intrinsic and extrinsic processes. These processes affect single cells to produce a fully integrated organism with distinct functional cell types and tissues. Experimental hematology provides insight into… read more here.
Keywords: hematology; functional hematopoietic; cell; hematopoietic stem ... See more keywords