Weighted Trigonometric Regression for Suboptimal Designs in Circadian Transcriptome Studies
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DOI: 10.1002/sim.70201
Abstract: Circadian transcriptome studies often use trigonometric regression to model gene expression over time. Ideally, protocols in these studies would collect tissue samples at evenly distributed and equally spaced time points over a 24‐hour period. This… read more here.
Keywords: circadian transcriptome; transcriptome studies; regression; weighted trigonometric ... See more keywords
Sex Inclusion in Transcriptome Studies of Daily Rhythms
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biological Rhythms"
DOI: 10.1101/2022.08.18.504312
Abstract: Biomedical research on mammals has traditionally neglected females, raising the concern that some scientific findings may generalize poorly to half the population. Although this lack of sex inclusion has been broadly documented, its extent within… read more here.
Keywords: transcriptome studies; sex; sex inclusion; daily rhythms ... See more keywords