Transcriptome‐wide association study identifies multiple genes and pathways associated with pancreatic cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Medicine"
DOI: 10.1002/cam4.1836
Abstract: To identify novel candidate genes for pancreatic cancer. read more here.
Keywords: study identifies; pancreatic cancer; transcriptome wide; cancer ... See more keywords
Some statistical consideration in transcriptome‐wide association studies
Sign Up to like & getrecommendations! Published in 2019 at "Genetic Epidemiology"
DOI: 10.1002/gepi.22274
Abstract: The methodology of transcriptome‐wide association studies (TWAS) has become popular in integrating a reference expression quantitative trait (eQTL) data set with an independent main GWAS data set to identify (putatively) causal genes, shedding mechanistic insights… read more here.
Keywords: trait; association; expression; transcriptome wide ... See more keywords
Investigation of prediction accuracy and the impact of sample size, ancestry, and tissue in transcriptome‐wide association studies
Sign Up to like & getrecommendations! Published in 2020 at "Genetic Epidemiology"
DOI: 10.1002/gepi.22290
Abstract: In transcriptome‐wide association studies (TWAS), gene expression values are predicted using genotype data and tested for association with a phenotype. The power of this approach to detect associations relies, at least in part, on the… read more here.
Keywords: accuracy; tissue; association; prediction accuracy ... See more keywords
Characterization of the sublethal toxicity and transcriptome-wide biological changes induced by λ-cyhalothrin in Bombyx mori.
Sign Up to like & getrecommendations! Published in 2023 at "Environmental toxicology"
DOI: 10.1002/tox.23798
Abstract: λ-Cyhalothrin (λ-cyh) is widely used in agricultural production and has been reported to cause damages to numerous nontarget insects. As an important economic and model insect of Lepidoptera, Bombyx mori was extremely sensitive to λ-cyh,… read more here.
Keywords: cyh; cyhalothrin; bombyx mori; transcriptome wide ... See more keywords
Transcriptome-Wide Profiling of RNA Stability.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1851-6_17
Abstract: Gene expression is controlled at multiple levels, including RNA transcription and turnover. But determining the relative contributions of RNA biogenesis and decay to the steady-state abundance of cellular transcripts remains challenging because conventional transcriptomics approaches… read more here.
Keywords: profiling rna; rna stability; transcriptome wide; wide profiling ... See more keywords
Transcriptome-Wide Mapping of N 1-Methyladenosine Methylome.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6807-7_16
Abstract: N 1-Methyladenosine (m1A) is a prevalent posttranscriptional RNA modification and commonly found in tRNA and rRNA. Very recent works have also demonstrated the prevalence of m1A in mammalian mRNA. Hence, high-throughput methods that allow transcriptome-wide… read more here.
Keywords: wide mapping; transcriptome wide; mapping methyladenosine; m1a ... See more keywords
Bisulfite Sequencing of RNA for Transcriptome-Wide Detection of 5-Methylcytosine.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8808-2_1
Abstract: A powerful method to determine the methylation status of specific cytosine residues within RNA is bisulfite sequencing. In combination with high-throughput sequencing methods cytosine methylation can be determined at nucleotide resolution on a transcriptome-wide level.… read more here.
Keywords: sequencing rna; bisulfite sequencing; rna transcriptome; wide detection ... See more keywords
Transcriptome-wide identification of indole glucosinolate dependent flg22-response genes in Arabidopsis.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.09.110
Abstract: Indole glucosinolates are known to play essential and diverse roles in Arabidopsis immunity to pathogens. However, a complete understanding of the function of these compounds in plant immunity remains unclear. In this study, we investigated… read more here.
Keywords: wide identification; myb51; immunity; identification indole ... See more keywords
The Transcriptome-wide Landscape and Modalities of EJC Binding in Adult Drosophila.
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.06.088
Abstract: Exon junction complex (EJC) assembles after splicing at specific positions upstream of exon-exon junctions in mRNAs of all higher eukaryotes, affecting major regulatory events. In mammalian cell cytoplasm, EJC is essential for efficient RNA surveillance,… read more here.
Keywords: wide landscape; adult drosophila; transcriptome wide; landscape modalities ... See more keywords
Transcriptome-wide Identification and Validation of Interactions between the miRNA Machinery and HuR on mRNA Targets.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2017.12.006
Abstract: The 3' untranslated region (UTR) of mRNAs is the primary regulatory region that mediates post-transcriptional control by microRNAs and RNA-binding proteins in the cytoplasm. Aside from individual sequence-specific binding and regulation, examples of interaction between… read more here.
Keywords: wide identification; identification validation; hur; validation interactions ... See more keywords
Transcriptome-wide identification and expression analysis of ERF family genes in Actinidia valvata during waterlogging stress
Sign Up to like & getrecommendations! Published in 2021 at "Scientia Horticulturae"
DOI: 10.1016/j.scienta.2021.109994
Abstract: Abstract Recently, there has been a tremendous increase in the cultivated area of kiwifruit in China. However, the low tolerance of most cultivars to waterlogging largely halted its expansion in waterlogged areas. Previously, some genotypes… read more here.
Keywords: expression; waterlogging stress; transcriptome wide; analysis ... See more keywords