Articles with "transcriptomic epigenetic" as a keyword



Longitudinal transcriptomic and epigenetic analysis of the blood in two astronauts

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Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-13383-8

Abstract: The space industry has made significant strides, leading to an era of commercial spaceflight. Meanwhile, understanding molecular responses to spaceflight is crucial for astronauts’ safety. To this end, we examined transcriptomic and epigenetic changes in… read more here.

Keywords: two astronauts; methylation; analysis; transcriptomic epigenetic ... See more keywords

Transcriptomic and epigenetic characterization of mucinous adenocarcinoma of the cervix.

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Published in 2024 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2024.42.16_suppl.e17518

Abstract: e17518 Background: Mucinous adenocarcinoma of the cervix (MAC) is a rare and aggressive histologic subtype of cervical cancer with poorer prognosis than its more common counterparts, usual type endocervical adenocarcinoma (UEA) and squamous cell carcinoma… read more here.

Keywords: mac; cancer; mucinous adenocarcinoma; transcriptomic epigenetic ... See more keywords

Transcriptomic and epigenetic preservation of genetic sex identity in estrogen-feminized male chicken embryonic gonads.

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Published in 2020 at "Endocrinology"

DOI: 10.1210/endocr/bqaa208

Abstract: Whereas in ovo exposure of genetically male (ZZ) chicken embryos to exogenous estrogens temporarily feminizes gonads at the time of hatching, the morphologically ovarian ZZ-gonads (FemZZs for feminized ZZ gonads) are masculinized back to testes… read more here.

Keywords: transcriptomic epigenetic; genetic sex; male chicken; sex ... See more keywords

Cancer-predicting transcriptomic and epigenetic signatures revealed for ulcerative colitis in patient-derived epithelial organoids

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Published in 2018 at "Oncotarget"

DOI: 10.18632/oncotarget.25617

Abstract: Ulcerative colitis (UC) is a prevalent form of inflammatory bowel disease (IBD) whose pathogenic mechanisms remain unclear. Elucidating these mechanisms is important to reduce UC symptoms and to prevent UC progression into colitis-associated colon cancer… read more here.

Keywords: transcriptomic epigenetic; cancer predicting; ulcerative colitis; cancer ... See more keywords

The prospect of genomic, transcriptomic, epigenetic and metabolomic biomarkers for the personalized prevention of type 2 diabetes and cardiovascular diseases.

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Published in 2023 at "Current vascular pharmacology"

DOI: 10.2174/1570161121666230510141338

Abstract: Cardiometabolic diseases, such as type 2 diabetes mellitus (DM) and cardiovascular disease (CVD), are a great health concern. The strategies aimed to increase awareness and prevention, in conjunction with timely diagnosis and optimal management of… read more here.

Keywords: metabolomic biomarkers; prevention; type diabetes; transcriptomic epigenetic ... See more keywords

Network Approaches for Charting the Transcriptomic and Epigenetic Landscape of the Developmental Origins of Health and Disease

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Published in 2022 at "Genes"

DOI: 10.3390/genes13050764

Abstract: The early developmental phase is of critical importance for human health and disease later in life. To decipher the molecular mechanisms at play, current biomedical research is increasingly relying on large quantities of diverse omics… read more here.

Keywords: transcriptomic epigenetic; health disease; network approaches;