Transcriptomic and epigenetic preservation of genetic sex identity in estrogen-feminized male chicken embryonic gonads.
Sign Up to like & getrecommendations! Published in 2020 at "Endocrinology"
DOI: 10.1210/endocr/bqaa208
Abstract: Whereas in ovo exposure of genetically male (ZZ) chicken embryos to exogenous estrogens temporarily feminizes gonads at the time of hatching, the morphologically ovarian ZZ-gonads (FemZZs for feminized ZZ gonads) are masculinized back to testes… read more here.
Keywords: transcriptomic epigenetic; genetic sex; male chicken; sex ... See more keywords
Cancer-predicting transcriptomic and epigenetic signatures revealed for ulcerative colitis in patient-derived epithelial organoids
Sign Up to like & getrecommendations! Published in 2018 at "Oncotarget"
DOI: 10.18632/oncotarget.25617
Abstract: Ulcerative colitis (UC) is a prevalent form of inflammatory bowel disease (IBD) whose pathogenic mechanisms remain unclear. Elucidating these mechanisms is important to reduce UC symptoms and to prevent UC progression into colitis-associated colon cancer… read more here.
Keywords: transcriptomic epigenetic; cancer predicting; ulcerative colitis; cancer ... See more keywords
The prospect of genomic, transcriptomic, epigenetic and metabolomic biomarkers for the personalized prevention of type 2 diabetes and cardiovascular diseases.
Sign Up to like & getrecommendations! Published in 2023 at "Current vascular pharmacology"
DOI: 10.2174/1570161121666230510141338
Abstract: Cardiometabolic diseases, such as type 2 diabetes mellitus (DM) and cardiovascular disease (CVD), are a great health concern. The strategies aimed to increase awareness and prevention, in conjunction with timely diagnosis and optimal management of… read more here.
Keywords: metabolomic biomarkers; prevention; type diabetes; transcriptomic epigenetic ... See more keywords
Network Approaches for Charting the Transcriptomic and Epigenetic Landscape of the Developmental Origins of Health and Disease
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13050764
Abstract: The early developmental phase is of critical importance for human health and disease later in life. To decipher the molecular mechanisms at play, current biomedical research is increasingly relying on large quantities of diverse omics… read more here.
Keywords: transcriptomic epigenetic; health disease; network approaches;