Transcriptomic landscape of mammalian ventral pallidum at single-cell resolution
Sign Up to like & getrecommendations! Published in 2024 at "Science Advances"
DOI: 10.1126/sciadv.adq6017
Abstract: The ventral pallidum (VP) is critical for motivated behaviors. While contemporary work has begun to elucidate the functional diversity of VP neurons, the molecular heterogeneity underlying this functional diversity remains incompletely understood. We used single-nucleus… read more here.
Keywords: transcriptomic landscape; ventral pallidum; cell; landscape mammalian ... See more keywords
The Oncogenic PI3K-Induced Transcriptomic Landscape Reveals Key Functions in Splicing and Gene Expression Regulation
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Research"
DOI: 10.1158/0008-5472.can-22-0446
Abstract: Transcriptomic analysis reveals a key role for the PI3K pathway in regulating RNA splicing, uncovering new mechanisms by which PI3K regulates proliferation and metabolism in breast cancer. read more here.
Keywords: pi3k; reveals key; induced transcriptomic; pi3k induced ... See more keywords
Transcriptomic landscape of Hras12V oncogene-induced hepatocarcinogenesis with gender disparity
Sign Up to like & getrecommendations! Published in 2025 at "BMC Cancer"
DOI: 10.1186/s12885-025-13476-7
Abstract: The genesis of hepatocellular carcinoma (HCC) is closely related to male factors and hyper-activated Ras signals. A transcriptomic database was established via RNA-Seq of HCC (T) and the adjacent precancerous liver tissue (P) of Hras12V… read more here.
Keywords: hras12v; oncogene induced; transcriptomic landscape; landscape hras12v ... See more keywords
Transcriptomic landscape of Kaposi sarcoma: Insights into therapeutic targeting of KSHV.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2025.43.16_suppl.e23526
Abstract: e23526 Background: Kaposi sarcoma (KS) is a tumor caused by Kaposi sarcoma herpesvirus (KSHV), also known as human herpesvirus 8 (HHV-8). Unlike other virus-associated tumors, where disease progression often continues even after viral eradication, KS… read more here.
Keywords: transcriptomic landscape; gene expression; kaposi sarcoma; lytic latent ... See more keywords
The transcriptomic landscape of elderly acute myeloid leukemia identifies B7H3 and BANP as a favorable signature in high-risk patients
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1054458
Abstract: Acute myeloid leukemia (AML) in the elderly remains a clinical challenge, with a five-year overall survival rate below 10%. The current ELN 2017 genetic risk classification considers cytogenetic and mutational characteristics to stratify fit AML… read more here.
Keywords: myeloid leukemia; signature; high risk; transcriptomic landscape ... See more keywords
The Transcriptomic Landscape of Pediatric Astrocytoma
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232012696
Abstract: Central nervous system tumors are the most common solid neoplasia during childhood and represent one of the leading causes of cancer-related mortality. Tumors arising from astrocytic cells (astrocytomas) are the most frequently diagnosed, and according… read more here.
Keywords: astrocytoma; grades astrocytoma; transcriptomic landscape; pediatric astrocytoma ... See more keywords
Effect of cryoablation on the spatial transcriptomic landscape of the immune microenvironment in non-small cell lung cancer.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of cancer research and therapeutics"
DOI: 10.4103/jcrt.jcrt_1887_24
Abstract: BACKGROUND Cryoablation induces antitumor immune responses. Spatial transcriptomic landscape technology has been used to determine the micron-level panoramic transcriptomics of tissue slices in situ. METHODS The effects of cryoablation on the immune microenvironment in non-small… read more here.
Keywords: cancer; transcriptomic landscape; cryoablation; spatial transcriptomic ... See more keywords