Transcriptomic Profiling Unveils EDN3 + Meningeal Fibroblasts as Key Players in Sturge‐Weber Syndrome Pathogenesis
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202408888
Abstract: Sturge‐Weber syndrome (SWS) is characterized by leptomeningeal vascular malformation, resulting in significant risks of life‐threatening seizures and strokes. The current absence of specific treatments underscores the need to define the molecular and cellular mechanisms that… read more here.
Keywords: profiling unveils; sws; weber syndrome; transcriptomic profiling ... See more keywords
Whole blood transcriptomic profiling identifies molecular pathways related to cardiovascular mortality in heart failure
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Heart Failure"
DOI: 10.1002/ejhf.2540
Abstract: Chronic heart failure (CHF) is a systemic syndrome with a poor prognosis and a need for novel therapies. We investigated whether whole blood transcriptomic profiling can provide new mechanistic insights into cardiovascular (CV) mortality in… read more here.
Keywords: blood transcriptomic; heart failure; transcriptomic profiling; whole blood ... See more keywords
Transcriptomic Profiling in Human Decidua of Severe Preeclampsia Detected by RNA Sequencing
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26221
Abstract: Maternal decidua plays a critical role in implantation and placentation. Impaired decidualization causes failed intravascular trophoblast invasion and inadequate placentation and then increases the risk of preeclampsia (PE). RNA sequencing (RNA‐Seq) has achieved great advances… read more here.
Keywords: transcriptomic profiling; human decidua; decidua; rna sequencing ... See more keywords
Transcriptomic Profiling Reveals 17β‐Estradiol Treatment Represses Ubiquitin‐Proteasomal Mediators in Skeletal Muscle of Ovariectomized Mice
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.13698
Abstract: With a decline of 17β‐estradiol (E2) at menopause, E2 has been implicated in the accompanied loss of skeletal muscle mass and strength. We aimed at characterizing transcriptomic responses of skeletal muscle to E2 in female… read more here.
Keywords: skeletal muscle; treatment; ovariectomized mice; muscle ... See more keywords
Transcriptomic Profiling of the Arabidopsis Embryonic Epidermis Using FANS in Combination with RNAseq.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0342-0_12
Abstract: The fundamental mechanisms of cell identity and tissue establishment are important already from the very beginning of a plant's life and reiterate later during development. In order to unravel and understand the underlying mechanisms to… read more here.
Keywords: arabidopsis embryonic; transcriptomic profiling; embryonic epidermis; tissue ... See more keywords
Small-bowel carcinomas associated with celiac disease: transcriptomic profiling shows predominance of microsatellite instability-immune and mesenchymal subtypes
Sign Up to like & getrecommendations! Published in 2019 at "Virchows Archiv"
DOI: 10.1007/s00428-019-02675-w
Abstract: Celiac disease (CD) is a risk factor for developing small-bowel carcinoma with a 14-fold higher risk compared with general population. As small-bowel carcinomas associated with CD (CD-SBCs) are extremely rare, very few molecular data are… read more here.
Keywords: small bowel; bowel; carcinomas associated; bowel carcinomas ... See more keywords
Global Transcriptomic Profiling of the Bone Marrow Stromal Microenvironment during Postnatal Development, Aging, and Inflammation.
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.11.004
Abstract: Bone marrow (BM) stromal cells provide the regulatory framework for hematopoiesis and contribute to developmental stage-specific niches, such as those preserving hematopoietic stem cells. Despite advances in our understanding of stromal function, little is known… read more here.
Keywords: global transcriptomic; marrow stromal; transcriptomic profiling; bone marrow ... See more keywords
Efficient Generation and Transcriptomic Profiling of Human iPSC-Derived Pulmonary Neuroendocrine Cells
Sign Up to like & getrecommendations! Published in 2020 at "iScience"
DOI: 10.1016/j.isci.2020.101083
Abstract: Summary Expansion of pulmonary neuroendocrine cells (PNECs) is a pathological feature of many human lung diseases. Human PNECs are inherently difficult to study due to their rarity ( read more here.
Keywords: neuroendocrine cells; efficient generation; pulmonary neuroendocrine; transcriptomic profiling ... See more keywords
Comparative transcriptomic profiling in HPV-associated cervical carcinogenesis: Implication of MHC class II and immunoglobulin heavy chain genes.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.118026
Abstract: AIM We aimed to determine the biological processes and pathways involved in cervical carcinogenesis associated with high-risk human papillomavirus (HPV) infection. MATERIALS AND METHODS Total RNA was extracted from three formalin-fixed paraffin-embedded (FFPE) samples each… read more here.
Keywords: immunoglobulin heavy; hpv; cervical carcinogenesis; transcriptomic profiling ... See more keywords
Single-Cell Transcriptomic Profiling of Pluripotent Stem Cell-Derived SCGB3A2+ Airway Epithelium
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DOI: 10.1016/j.stemcr.2018.03.013
Abstract: Summary Lung epithelial lineages have been difficult to maintain in pure form in vitro, and lineage-specific reporters have proven invaluable for monitoring their emergence from cultured pluripotent stem cells (PSCs). However, reporter constructs for tracking… read more here.
Keywords: single cell; transcriptomic profiling; stem cell; pluripotent stem ... See more keywords
Transcriptomic profiling of cotton Gossypium hirsutum challenged with low-temperature gradients stress
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Data"
DOI: 10.1038/s41597-019-0210-7
Abstract: AbstractGossypium hirsutum, a cotton species widely cultivated around the world, is a typical cold-sensitive crop. Low-temperature (LT) stress is one of the main environmental stressors that can affect growth and the quality of cotton fibers.… read more here.
Keywords: quality; low temperature; temperature; hirsutum ... See more keywords