Integrated transcriptomic and proteomic analysis of the ethanol stress response in Saccharomyces cerevisiae Sc131.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of proteomics"
DOI: 10.1016/j.jprot.2019.103377
Abstract: The molecular mechanism of Saccharomyces cerevisiae tolerant to ethanol stress remains to be further elucidated. In this study, a comprehensive analysis based on RNA-seq and iTRAQ LC-MS/MS was used to investigate the global mechanism of… read more here.
Keywords: response; ethanol stress; analysis; transcriptomic proteomic ... See more keywords
Transcriptomic and proteomic profiling of glial versus neuronal Dube3a overexpression reveals common molecular changes in gliopathic epilepsies
Sign Up to like & getrecommendations! Published in 2020 at "Neurobiology of Disease"
DOI: 10.1016/j.nbd.2020.104879
Abstract: Epilepsy affects millions of individuals worldwide and many cases are pharmacoresistant. Duplication 15q syndrome (Dup15q) is a genetic disorder caused by duplications of the 15q11.2-q13.1 region. Phenotypes include in a high rate of pharmacoresistant epilepsy.… read more here.
Keywords: epilepsy; dube3a; repo dube3a; dube3a overexpression ... See more keywords
Transcriptomic and proteomic signatures of stemness and differentiation in the colon crypt
Sign Up to like & getrecommendations! Published in 2020 at "Communications Biology"
DOI: 10.1038/s42003-020-01181-z
Abstract: Intestinal stem cells are non-quiescent, dividing epithelial cells that rapidly differentiate into progenitor cells of the absorptive and secretory cell lineages. The kinetics of this process is rapid such that the epithelium is replaced weekly.… read more here.
Keywords: cell; proteomic signatures; colon; transcriptomic proteomic ... See more keywords
Revealing new insights into different phosphorus-starving responses between two maize (Zea mays) inbred lines by transcriptomic and proteomic studies
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep44294
Abstract: Phosphorus (P) is an essential plant nutrient, and deficiency of P is one of the most important factors restricting maize yield. Therefore, it is necessary to develop a more efficient program of P fertilization and… read more here.
Keywords: phosphorus; transcriptomic proteomic; revealing new; new insights ... See more keywords
Latent Mn deficiency in maize is aggravated by high light intensity as revealed by physiological, transcriptomic and proteomic analyses.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of experimental botany"
DOI: 10.1093/jxb/eraa366
Abstract: Manganese (Mn) plays an important role in the oxygen-evolving complex, where energy from light absorption is used for water splitting. Although changes in light intensity and Mn status can interfere with the functionality of the… read more here.
Keywords: high light; latent deficiency; light intensity; intensity ... See more keywords
Unified epigenomic, transcriptomic, proteomic, and metabolomic taxonomy of Alzheimer’s disease progression and heterogeneity
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abo6764
Abstract: Alzheimer’s disease (AD) is a heterogeneous disorder with abnormalities in multiple biological domains. In an advanced machine learning analysis of postmortem brain and in vivo blood multi-omics molecular data (N = 1863), we integrated epigenomic,… read more here.
Keywords: epigenomic transcriptomic; alzheimer disease; proteomic metabolomic; taxonomy ... See more keywords
Transcriptomic and Proteomic of Gastrocnemius Muscle in Peripheral Artery Disease
Sign Up to like & getrecommendations! Published in 2023 at "Circulation Research"
DOI: 10.1161/circresaha.122.322325
Abstract: Background: Few effective therapies exist to improve lower extremity muscle pathology and mobility loss due to peripheral artery disease (PAD), in part because mechanisms associated with functional impairment remain unclear. Methods: To better understand mechanisms… read more here.
Keywords: non pad; gastrocnemius muscle; artery disease; muscle ... See more keywords
Transcriptomic and proteomic analyses reveal age-related extracellular matrix changes in the lung
Sign Up to like & getrecommendations! Published in 2020 at "ERJ Open Research"
DOI: 10.1183/23120541.lsc-2020.57
Abstract: Background: Beyond its principal role as physical support, the lung extracellular matrix (ECM) is a bioactive scaffold involved in numerous biological processes including cellular growth, migration, survival, differentiation and metabolism. Detailed knowledge on the differences… read more here.
Keywords: age related; age; extracellular matrix; transcriptomic proteomic ... See more keywords
Integration of transcriptomic and proteomic analyses reveals several levels of metabolic regulation in the excess starch and early senescent leaf mutant lses1 in rice
Sign Up to like & getrecommendations! Published in 2022 at "BMC Plant Biology"
DOI: 10.1186/s12870-022-03510-2
Abstract: Background The normal metabolism of transitory starch in leaves plays an important role in ensuring photosynthesis, delaying senescence and maintaining high yield in crops. OsCKI1 (casein kinase I1) plays crucial regulatory roles in multiple important… read more here.
Keywords: leaf; starch; lses1; rice ... See more keywords
Dysregulation of Synaptic and Developmental Transcriptomic/Proteomic Profiles upon Depletion of MUNC18-1
Sign Up to like & getrecommendations! Published in 2022 at "eNeuro"
DOI: 10.1523/eneuro.0186-22.2022
Abstract: Abstract Absence of presynaptic protein MUNC18-1 (gene: Stxbp1) leads to neuronal cell death at an immature stage before synapse formation. Here, we performed transcriptomic and proteomic profiling of immature Stxbp1 knock-out (KO) cells to discover… read more here.
Keywords: depletion; munc18; synaptic developmental; dysregulation synaptic ... See more keywords
Integrated Transcriptomic and Proteomic Analyses Reveal the Role of NprR in Bacillus anthracis Extracellular Protease Expression Regulation and Oxidative Stress Responses
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2020.590851
Abstract: NprR is a protein of Bacillus anthracis that exhibits moonlighting functions as either a phosphatase or a neutral protease regulator that belongs to the RNPP family. We previously observed that the extracellular protease activity of… read more here.
Keywords: deletion mutant; nprr deletion; protease; integrated transcriptomic ... See more keywords