Transcriptomics, proteomics, and metabolomics interventions prompt crop improvement against metal(loid) toxicity
Sign Up to like & getrecommendations! Published in 2024 at "Plant Cell Reports"
DOI: 10.1007/s00299-024-03153-7
Abstract: The escalating challenges posed by metal(loid) toxicity in agricultural ecosystems, exacerbated by rapid climate change and anthropogenic pressures, demand urgent attention. Soil contamination is a critical issue because it significantly impacts crop productivity. The widespread… read more here.
Keywords: loid toxicity; proteomics metabolomics; metal loid; transcriptomics proteomics ... See more keywords
Integrated transcriptomics and proteomics revealed the distinct toxicological effects of multi-metal contamination on oysters.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental pollution"
DOI: 10.1016/j.envpol.2021.117533
Abstract: The Pearl River Estuary (PRE) is the largest estuary in southern China and under high metal stress. In the present study, we employed an integrated method of transcriptomics and proteomics to investigate the ecotoxicological effects… read more here.
Keywords: station; transcriptomics proteomics; proteomics revealed; metal stress ... See more keywords
Dataset of the rumen microbiota and epithelial transcriptomics and proteomics in goat affected by solid diets
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Data"
DOI: 10.1038/s41597-024-03584-7
Abstract: Although early solid diet supplementation is a common practice to improve the growth and development in goat kids, its biological mechanism how solid diet induces rumen microbiota and epithelial development is still unknow. In this… read more here.
Keywords: dataset rumen; solid diet; transcriptomics proteomics; microbiota epithelial ... See more keywords
Cryogenic mouse tissue homogenization as an alternative to fresh-frozen biopsy use for genomics, transcriptomics, proteomics and metabolomics
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-06438-3
Abstract: The classical approach of using adjacent pieces of fresh-frozen tissue for various omics analysis from the same sample possesses a risk of biological mismatch between arising from intrinsic tissue heterogeneity. We propose an alternative approach… read more here.
Keywords: proteomics metabolomics; fresh frozen; transcriptomics proteomics; genomics transcriptomics ... See more keywords
Transcriptomics and Proteomics Methods for Xenopus Embryos and Tissues.
Sign Up to like & getrecommendations! Published in 2019 at "Cold Spring Harbor protocols"
DOI: 10.1101/pdb.top098350
Abstract: The general field of quantitative biology has advanced significantly on the back of recent improvements in both sequencing technology and proteomics methods. The development of high-throughput, short-read sequencing has revolutionized RNA-based expression studies, while improvements… read more here.
Keywords: transcriptomics proteomics; xenopus embryos; proteomics methods; methods xenopus ... See more keywords
Recent advances of transcriptomics and proteomics in triple‐negative breast cancer prognosis assessment
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17124
Abstract: Triple‐negative breast cancer (TNBC), a heterogeneous tumour that lacks the expression of oestrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2), is often characterized by aggressiveness and tends to recur… read more here.
Keywords: triple negative; negative breast; breast cancer; transcriptomics proteomics ... See more keywords
Genomics, transcriptomics and proteomics: enabling insights into social evolution and disease challenges for managed and wild bees
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Ecology"
DOI: 10.1111/mec.13986
Abstract: Globally, there are over 20 000 bee species (Hymenoptera: Apoidea: Anthophila) with a host of biologically fascinating characteristics. Although they have long been studied as models for social evolution, recent challenges to bee health (mainly… read more here.
Keywords: evolution; transcriptomics proteomics; enabling insights; genomics transcriptomics ... See more keywords
Combined transcriptomics and proteomics unveil the impact of vitamin C in modulating specific protein abundance in the mouse liver
Sign Up to like & getrecommendations! Published in 2024 at "Biological Research"
DOI: 10.1186/s40659-024-00509-x
Abstract: Background Vitamin C (ascorbate) is a water-soluble antioxidant and an important cofactor for various biosynthetic and regulatory enzymes. Mice can synthesize vitamin C thanks to the key enzyme gulonolactone oxidase (Gulo) unlike humans. In the… read more here.
Keywords: vitamin; transcriptomics proteomics; liver; impact vitamin ... See more keywords
Integrated analysis of transcriptomics, proteomics and metabolomics data reveals the role of SLC39A1 in renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.977960
Abstract: Purpose: Accumulating evidence suggests that solute carrier family 39 member 1 (SLC39A1) conceivably function as a tumor suppressor, but the underlying mechanism in renal cell carcinoma (RCC) is poorly understood. Methods: OSRC-2 renal cancer cells… read more here.
Keywords: cell; cell carcinoma; metabolism; renal cell ... See more keywords
Integration of transcriptomics, proteomics, and metabolomics data for the detection of the human pathogenic Prototheca wickerhamii from a One Health perspective
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2023.1152198
Abstract: Prototheca species are the only microalgae known to cause opportunistic infections in vertebrates and humans. Most cases of protothecosis in humans are caused by Prototheca wickerhamii, but knowledge of the pathogenicity and biology of Prototheca… read more here.
Keywords: health perspective; transcriptomics proteomics; proteomics metabolomics; prototheca ... See more keywords
Integration of transcriptomics, proteomics, and metabolomics data to reveal HER2-associated metabolic heterogeneity in gastric cancer with response to immunotherapy and neoadjuvant chemotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.951137
Abstract: Background Currently available prognostic tools and focused therapeutic methods result in unsatisfactory treatment of gastric cancer (GC). A deeper understanding of human epidermal growth factor receptor 2 (HER2)-coexpressed metabolic pathways may offer novel insights into… read more here.
Keywords: transcriptomics proteomics; proteomics metabolomics; her2; gastric cancer ... See more keywords