Articles with "transcutaneous immunization" as a keyword



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Transcutaneous immunization of Streptococcus suis bacterin using dissolving microneedles.

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Published in 2017 at "Comparative immunology, microbiology and infectious diseases"

DOI: 10.1016/j.cimid.2016.12.001

Abstract: Vaccine delivery using microneedle (MN) patches is an easy, safe and painless alternative to traditional needle injections. In this study, we examined whether MN patches can enhance the efficacy of a Streptococcus suis serotype 2… read more here.

Keywords: immunization streptococcus; streptococcus suis; transcutaneous immunization; suis bacterin ... See more keywords
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Overcoming or circumventing the stratum corneum barrier for efficient transcutaneous immunization.

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Published in 2018 at "Drug discovery today"

DOI: 10.1016/j.drudis.2017.09.017

Abstract: Transcutaneous immunization (TCI) is a promising alternative to vaccine delivery via the subcutaneous and intramuscular routes because of the unique immunological characteristics of the skin. However, the stratum corneum (SC) prevents entry of most therapeutic… read more here.

Keywords: circumventing stratum; stratum corneum; transcutaneous immunization; overcoming circumventing ... See more keywords
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Combined immunotherapy: CTLA-4 blockade potentiates anti-tumor response induced by transcutaneous immunization.

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Published in 2017 at "Journal of dermatological science"

DOI: 10.1016/j.jdermsci.2017.06.013

Abstract: BACKGROUND The epidermal application of the Toll Like Receptor 7 agonist imiquimod and a T-cell peptide epitope (transcutaneous immunization, TCI) mediates systemic peptide-specific cytotoxic T-cell (CTL) responses and leads to tumor protection in a prophylactic… read more here.

Keywords: tumor; response; ctla; transcutaneous immunization ... See more keywords