Articles with "transdermal delivery" as a keyword



Ionic Liquid‐Mediated Transdermal Delivery of Thrombosis‐Detecting Nanosensors

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Published in 2022 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202102685

Abstract: Blood clotting disorders such as pulmonary embolism are associated with high morbidity and mortality. A large portion of thrombotic events occur postoperative and after hospital discharge. Therefore, easily applicable, noninvasive, and long‐term monitoring of thrombosis… read more here.

Keywords: liquid mediated; pulmonary embolism; ionic liquid; transdermal delivery ... See more keywords
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Transdermal Delivery of Photosensitizer-Catalase Conjugate by Fluorinated Polyethylenimine for Enhanced Topical Photodynamic Therapy of Bacterial Infections.

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Published in 2023 at "Advanced healthcare materials"

DOI: 10.1002/adhm.202300848

Abstract: Pathogenic bacteria induced subcutaneous infections pose serious threats to global public health. Recently, photodynamic therapy (PDT) has been proposed as a non-invasive approach for anti-microbial treatment, without the risk to induce drug-resistance. However, due to… read more here.

Keywords: catalase; photodynamic therapy; transdermal delivery; delivery ... See more keywords

Heat-Responsive Phase-Change Cream Broadly Enhances Transdermal Delivery Through a Mild Photothermal Strategy.

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Published in 2025 at "Advanced materials"

DOI: 10.1002/adma.202416017

Abstract: High‐temperature‐mediated transdermal delivery often relies on extreme heating to disrupt the skin barrier, but these approaches risk tissue damage and drug denaturation. Mild thermal stimulation promises safer uptake, yet achieving precise temperature control is inconvenient,… read more here.

Keywords: heat responsive; delivery; cream; transdermal delivery ... See more keywords

Bioactive Glycyrrhizic Acid Ionic Liquid Self‐Assembled Nanomicelles for Enhanced Transdermal Delivery of Anti‐Photoaging Signal Peptides

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Published in 2025 at "Advanced Science"

DOI: 10.1002/advs.202412581

Abstract: Sigal peptides have garnered remarkable efficacy in rejuvenating photoaged skin and delaying senescence. Nevertheless, their low solubility and poor permeability bring about a formidable challenge in their transdermal delivery. To address this challenge, bioactive ionic… read more here.

Keywords: transdermal delivery; self assembled; anti photoaging; glycyrrhizic acid ... See more keywords

Polymeric Microneedles for Transdermal Delivery of Human Placental Tissue for the Treatment of Osteoarthritis

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Published in 2024 at "Macromolecular Bioscience"

DOI: 10.1002/mabi.202400485

Abstract: Biologics targeting matrix‐degrading proteases, cartilage repair, and inflammation are emerging as promising approaches for osteoarthritis (OA) treatment. Recent research highlights biologic‐human placental tissue (HPT) as a potential OA therapy due to its biocompatibility, abundant protein… read more here.

Keywords: treatment; placental tissue; delivery; human placental ... See more keywords

Recent advances in polymer microneedles for drug transdermal delivery: Design strategies and applications.

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Published in 2022 at "Macromolecular rapid communications"

DOI: 10.1002/marc.202200037

Abstract: In recent years, the transdermal drug delivery based on microneedles (MNs) technology has received extensive attention, which offers a safer and painless alternative to hypodermic needle injection. They can pierce the stratum corneum and deliver drugs… read more here.

Keywords: drug transdermal; polymer mns; transdermal delivery; drug ... See more keywords

Hyperbranched Macromonomer‐Based Gelation of Hyaluronic Acid for Efficient Liposome Encapsulation and Improved Transdermal Delivery

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Published in 2025 at "Macromolecular Rapid Communications"

DOI: 10.1002/marc.202500310

Abstract: Liposome‐based formulations, while facilitating drug penetration across physiological barriers, face considerable challenges, including instability, rapid clearance in vivo, and inadequate control over drug release. Incorporating liposomes into hydrogels presents a promising approach to enhancing stability… read more here.

Keywords: delivery; hyaluronic acid; drug; liposome encapsulation ... See more keywords
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Transdermal Delivery of Nucleic Acid Mediated by Punching and Electroporation.

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Published in 2020 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-9740-4_11

Abstract: Transdermal delivery of gene medicine holds a great promise in gene therapy, and electroporation-mediated method is a high-efficiency drug transfer technique. Traditional skin electroporation approaches require high voltage that may cause severe injure. In this… read more here.

Keywords: transdermal delivery; nucleic acid; delivery; electroporation ... See more keywords

On the Road to Development of an in Vitro Permeation Test (IVPT) Model to Compare Heat Effects on Transdermal Delivery Systems: Exploratory Studies with Nicotine and Fentanyl

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Published in 2017 at "Pharmaceutical Research"

DOI: 10.1007/s11095-017-2189-0

Abstract: PurposeAt elevated temperatures, the rate of drug release and skin permeation from transdermal delivery systems (TDS) may be higher than at a normal skin temperature. The aim of this study was to compare the effect… read more here.

Keywords: transdermal delivery; permeation; delivery; delivery systems ... See more keywords

Synergistic Transdermal Delivery of Biomacromolecules Using Sonophoresis after Microneedle Treatment

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Published in 2018 at "Biotechnology and Bioprocess Engineering"

DOI: 10.1007/s12257-018-0070-6

Abstract: Transdermal drug delivery systems have been studied as an attractive alternative to conventional delivery routes. However, the outermost layer of the skin, the stratum corneum, acts as a primary barrier to drug delivery. A synergistic… read more here.

Keywords: synergistic transdermal; transdermal delivery; delivery biomacromolecules; drug delivery ... See more keywords

Radiation preparation of l-arginine/acrylic acid hydrogel matrix patch for transdermal delivery of propranolol HCl in hypertensive rats

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Published in 2017 at "Drug Delivery and Translational Research"

DOI: 10.1007/s13346-017-0468-2

Abstract: In the present study, l-arginine/acrylic acid (Arg/AAc) batch hydrogel was successfully prepared by gamma irradiation for transdermal delivery of propranolol HCl in hypertensive rats. The resulted system has been characterized by FTIR to confirm the… read more here.

Keywords: transdermal delivery; arginine acrylic; hydrogel; hypertensive rats ... See more keywords