Pharmacokinetics, Pharmacodynamics, and Safety of a Single Escalating Dose and Repeated Doses of Rasagiline Transdermal Patch in Healthy Chinese Subjects
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.761
Abstract: A rasagiline transdermal patch can be used to offer continuous rasagiline to patients with Parkinson's disease who cannot take their usual oral medications. This was the first study to investigate the pharmacokinetics, pharmacodynamics, and safety… read more here.
Keywords: pharmacodynamics safety; patch; transdermal patch; rasagiline transdermal ... See more keywords
Impact of bisoprolol transdermal patch on early recurrence during the blanking period after atrial fibrillation ablation
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Arrhythmia"
DOI: 10.1002/joa3.12538
Abstract: Early recurrences of atrial arrhythmias (ERAAs) after ablation may require therapeutic intervention. The optimal medical therapy that prevents ERAAs requires clarification. This study aimed to compare the incidence of ERAAs between patients who received or… read more here.
Keywords: impact bisoprolol; early recurrence; ablation; transdermal patch ... See more keywords
Rotigotine transdermal patch for the treatment of neuropsychiatric symptoms in Parkinson's disease: A meta-analysis of randomized placebo-controlled trials
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Neurological Sciences"
DOI: 10.1016/j.jns.2018.08.003
Abstract: OBJECTIVE To systematically evaluate and quantify the effects of rotigotine treatment on neuropsychiatric symptoms in Parkinson's disease (PD). METHODS We searched for articles involving randomized controlled trials (RCTs) that were published before September 1, 2017,… read more here.
Keywords: pdq; treatment; neuropsychiatric symptoms; rotigotine transdermal ... See more keywords
Mussel-Inspired Adhesive Hydrogels Based on Laponite-Confined Dopamine Polymerization as a Transdermal Patch.
Sign Up to like & getrecommendations! Published in 2023 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c01168
Abstract: Transdermal patch for local drug delivery has attained huge attention as an attractive alternative to existing drug delivery techniques as it is painless and user-friendly. However, most adhesive hydrogels either do not have adequate adhesion… read more here.
Keywords: pda; pda hydrogel; pva pda; transdermal patch ... See more keywords
Bisoprolol transdermal patch improves orthostatic hypotension in patients with chronic heart failure and hypertension
Sign Up to like & getrecommendations! Published in 2020 at "Clinical and Experimental Hypertension"
DOI: 10.1080/10641963.2020.1723616
Abstract: ABSTRACT Ī² blockers (BBs) play an important role in heart failure (HF) treatment. However, orthostatic hypotension (OH) is sometimes caused by BBs. The bisoprolol transdermal patch works more slowly and is long acting compared with… read more here.
Keywords: patch; transdermal patch; hypertension; bisoprolol transdermal ... See more keywords
Analgesic impact of buprenorphine transdermal patch in total hip arthroplasty
Sign Up to like & getrecommendations! Published in 2020 at "Medicine"
DOI: 10.1097/md.0000000000020405
Abstract: Abstract Background: The efficacy and safety of buprenorphine transdermal patch (BTP) has been well established in chronic pain, but data regarding acute postoperative pain relief is still very limited. Therefore, we design a prospective, randomized,… read more here.
Keywords: hip arthroplasty; total hip; buprenorphine transdermal; transdermal patch ... See more keywords
Solid-State Stability Issues of Drugs in Transdermal Patch Formulations
Sign Up to like & getrecommendations! Published in 2017 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-017-0865-3
Abstract: The transdermal patch formulation has many advantages, including noninvasiveness, an ability to bypass the first-pass metabolism, low dosage requirements, and prolonged drug delivery. However, the instability of solid-state drugs is one of the most critical… read more here.
Keywords: transdermal patch; patch; state stability; solid state ... See more keywords
Development of novel pH-sensitive nanoparticle-based transdermal patch for management of rheumatoid arthritis.
Sign Up to like & getrecommendations! Published in 2020 at "Nanomedicine"
DOI: 10.2217/nnm-2019-0385
Abstract: Aim: To formulate and evaluate a pH-responsive nanoparticle (NP)-based patch for efficient transdermal delivery of flurbiprofen against rheumatoid arthritis. MaterialsĀ & methods: Nanoprecipitation technique was used for preparation of NPs and central composite design was employed… read more here.
Keywords: patch; transdermal patch; nanoparticle based; based transdermal ... See more keywords
Evaluation of the Structural Modification of Ibuprofen on the Penetration Release of Ibuprofen from a Drug-in-Adhesive Matrix Type Transdermal Patch
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23147752
Abstract: This study aimed to evaluate the effect of chemical modifications of the structure of active compounds on the skin permeation and accumulation of ibuprofen [IBU] from the acrylic pressure-sensitive adhesive used as a drug-in-adhesives matrix… read more here.
Keywords: ibuprofen; transdermal patch; ibu; type transdermal ... See more keywords
Manufacturing of a Transdermal Patch in 3D Printing
Sign Up to like & getrecommendations! Published in 2022 at "Micromachines"
DOI: 10.3390/mi13122190
Abstract: Diabetes mellitus is an endocrine disorder that affects glucose metabolism, making the body unable to effectively use the insulin it produces. Transdermal drug delivery (TDD) has attracted strong interest from researchers, as it allows minimally… read more here.
Keywords: manufacturing transdermal; transdermal patch; patch printing; delivery ... See more keywords
Effective Therapeutic Delivery and Bioavailability Enhancement of Pioglitazone Using Drug in Adhesive Transdermal Patch
Sign Up to like & getrecommendations! Published in 2019 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics11070359
Abstract: The administration of pioglitazone as an oral therapy is restricted due to various challenges. The aim of the current investigation was to evaluate the suitability of pioglitazone in adhesive transdermal patch as an alternative delivery… read more here.
Keywords: pioglitazone; adhesive transdermal; delivery; patch ... See more keywords