Janus kinase-signal transducers and activators of transcription cell signaling in Spondyloarthritis: rationale and evidence for JAK inhibition.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in rheumatology"
DOI: 10.1097/bor.0000000000000810
Abstract: PURPOSE OF REVIEW The Janus kinase-signal transducers and activators of transcription (JAK-STAT) signaling proteins represent a group of intracellular kinase molecules that play a central role in the signaling pathways induced by cytokines, chemokines, and… read more here.
Keywords: signal transducers; activators transcription; janus kinase; kinase signal ... See more keywords
Hybridization Approach to Identify Salicylanilides as Inhibitors of Tubulin Polymerization and Signal Transducers and Activators of Transcription 3 (STAT3)
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15070835
Abstract: The superimposition of the X-ray complexes of cyclohexanediones (i.e., TUB015), described by our research group, and nocodazole, within the colchicine binding site of tubulin provided an almost perfect overlap of both ligands. This structural information… read more here.
Keywords: activators transcription; transducers activators; signal transducers; transcription stat3 ... See more keywords