A transepithelial pathway delivers succinate to macrophages, thus perpetuating their pro-inflammatory metabolic state.
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DOI: 10.1016/j.celrep.2021.109521
Abstract: The gut metabolite composition determined by the microbiota has paramount impact on gastrointestinal physiology. However, the role that bacterial metabolites play in communicating with host cells during inflammatory diseases is poorly understood. Here, we aim… read more here.
Keywords: transepithelial pathway; succinate; pathway delivers; delivers succinate ... See more keywords