Stereoselective pH Responsive Peptide Dendrimers for siRNA Transfection.
Sign Up to like & getrecommendations! Published in 2019 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.9b00403
Abstract: Transfecting nucleic acids into cells is an essential procedure in biological research usually performed using nonviral transfection reagents. Unfortunately, most transfection reagents have polymeric or undisclosed structures and require nonstandard synthetic procedures. Herein we report… read more here.
Keywords: transfection; transfection reagents; sirna transfection; stereoselective responsive ... See more keywords
Microfluidic production of nanogels as alternative triple transfection reagents for the manufacture of adeno-associated virus vectors.
Sign Up to like & getrecommendations! Published in 2023 at "Nanoscale"
DOI: 10.1039/d2nr06401d
Abstract: Adeno-associated viral vectors (AAVs) have proved a mainstay in gene therapy, owing to their remarkable transduction efficiency and safety profile. Their production, however, remains challenging in terms of yield, the cost-effectiveness of manufacturing procedures and… read more here.
Keywords: pei max; production; adeno associated; transfection reagents ... See more keywords
Combinational use of lipid-based reagents for efficient transfection of primary fibroblasts and hepatoblasts.
Sign Up to like & getrecommendations! Published in 2017 at "BioTechniques"
DOI: 10.2144/000114569
Abstract: Commercially available lipid-based transfection reagents are widely used to deliver DNA to cells. However, these lipid-based transfection reagents show poor gene transfer efficiency in primary cells. Here, we demonstrate a simple method to improve gene… read more here.
Keywords: transfection; primary fibroblasts; transfection reagents; lipid based ... See more keywords