Efficacy of hydrodynamic interleukin 10 gene transfer in human liver segments with interest in transplantation
Sign Up to like & getrecommendations! Published in 2017 at "Liver Transplantation"
DOI: 10.1002/lt.24667
Abstract: Different diseases lead, during their advanced stages, to chronic or acute liver failure, whose unique treatment consists in organ transplantation. The success of intervention is limited by host immune response and graft rejection. The use… read more here.
Keywords: transfer human; liver; transplantation; gene transfer ... See more keywords
Mitochondrial replacement by genome transfer in human oocytes: Efficacy, concerns, and legality
Sign Up to like & getrecommendations! Published in 2021 at "Reproductive Medicine and Biology"
DOI: 10.1002/rmb2.12356
Abstract: Pathogenic mitochondrial (mt)DNA mutations, which often cause life‐threatening disorders, are maternally inherited via the cytoplasm of oocytes. Mitochondrial replacement therapy (MRT) is expected to prevent second‐generation transmission of mtDNA mutations. However, MRT may affect the… read more here.
Keywords: replacement; mitochondrial replacement; human oocytes; replacement genome ... See more keywords
Expansion and Adoptive Transfer of Human Vδ2+ T Cells to Assess Antitumor Effects In Vivo.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8885-3_4
Abstract: Recent clinical trials have yielded promising results suggesting that γδ T cell62-based immunotherapies can be effective against hematological malignancies. Human T cells expressing Vγ9Vδ2+ receptors are particularly attractive candidates for this application, since they can… read more here.
Keywords: expansion adoptive; cells assess; adoptive transfer; transfer human ... See more keywords
Mitochondrial Transfer into Human Oocytes Improved Embryo Quality and Clinical Outcomes in Recurrent Pregnancy Failure Cases
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032738
Abstract: One of the most critical issues to be solved in reproductive medicine is the treatment of patients with multiple failures of assisted reproductive treatment caused by low-quality embryos. This study investigated whether mitochondrial transfer to… read more here.
Keywords: quality; human oocytes; mitochondrial transfer; embryo quality ... See more keywords