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   Articles with "transfer inhibitors" as a keyword



Maternal Use of Integrase Strand Transfer Inhibitors During Pregnancy and Infant Neurodevelopment

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recommendations! Published in 2025 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2025.45652

Abstract: Key Points Question Do integrase strand transfer inhibitors (INSTIs) used as part of antiretroviral treatment (ART) by pregnant women with HIV have an adverse association with their infant’s neurodevelopment? Findings In this cohort study of… read more here.

Keywords: infant neurodevelopment; strand transfer; integrase strand; transfer inhibitors ... See more keywords

Integrase strand transfer inhibitors use in children with perinatal HIV-1 infection: a narrative review.

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recommendations! Published in 2022 at "AIDS research and human retroviruses"

DOI: 10.1089/aid.2022.0039

Abstract: INTRODUCTION Integrase strand transfer inhibitors (INSTIs), including raltegravir (RAL), dolutegravir (DTG), elvitegravir (EVG), bictegravir (BIC), and cabotegravir (CAB), are increasingly used given excellent data on their efficacy, effectiveness, and tolerability profile in adults, while data… read more here.

Keywords: integrase strand; strand transfer; transfer inhibitors; narrative review ... See more keywords

Resistance in Patients Failing Integrase Strand Transfer Inhibitors: A Call to Replace Raltegravir With Dolutegravir in Third-Line Treatment in South Africa

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recommendations! Published in 2019 at "Open Forum Infectious Diseases"

DOI: 10.1093/ofid/ofz377

Abstract: Abstract Data on integrase resistance patterns in low- and middle-income countries (LMICs) is scarce. We assessed genotypic drug resistance in 43 patients with virological failure on integrase strand transfer inhibitors (INSTIs) containing regimens as part… read more here.

Keywords: integrase; resistance patients; strand transfer; transfer inhibitors ... See more keywords

Integrase strand transfer inhibitors, their impact in adipose tissue and weight gain in people living with HIV - A narrative review.

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recommendations! Published in 2025 at "Nutricion hospitalaria"

DOI: 10.20960/nh.05562

Abstract: Greater weight gain following initiation of antiretroviral therapy (ART) with integrase strand transfer inhibitors (INsTI) compared with that seen with other classes of antiretroviral drugs, is an increasingly recognized problem in people living with HIV… read more here.

Keywords: strand transfer; weight gain; gain; integrase strand ... See more keywords