Hydride transfer initiated ring expansion of pyrrolidines toward highly functionalized tetrahydro-1-benzazepines.
Sign Up to like & getrecommendations! Published in 2018 at "Chemical communications"
DOI: 10.1039/c8cc08238c
Abstract: A novel hydride transfer initiated ring expansion of 4-pyrrolidinyl isatins to synthesize tetrahydro-1-benzazepines has been developed. This methodology represents an atom- and step-economical protocol to assemble seven-membered polycyclic amines from pyrrolidine derivatives in one step. read more here.
Keywords: initiated ring; ring expansion; tetrahydro benzazepines; transfer initiated ... See more keywords
Hydride transfer-initiated synthesis of 3-functionalized quinolines by deconstruction of isoquinoline derivatives.
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DOI: 10.1039/d2cc00127f
Abstract: Under transition metal catalyst-free conditions, we herein present a hydride transfer-initiated construction of novel 3-(2-aminomethyl)aryl quinolines from N-isoquinolinium salts and 2-aminobenzaldehydes, proceeding with the merits of operational simplicity, high step and atom efficiency, good substrate… read more here.
Keywords: synthesis functionalized; initiated synthesis; functionalized quinolines; transfer initiated ... See more keywords