Independent Generation of Reactive Intermediates Leads to an Alternative Mechanism for Strand Damage Induced by Hole Transfer in Poly(dA-T) Sequences.
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DOI: 10.1021/jacs.8b05484
Abstract: Purine radical cations (dA•+ and dG•+) are the primary hole carriers of DNA hole migration due to their favorable oxidation potential. Much less is known about the reactivity of higher energy pyrimidine radical cations. The… read more here.
Keywords: transfer poly; mechanism; transfer; poly sequences ... See more keywords