O‐GlcNAc Transferase: Structural Characteristics, Catalytic Mechanism and Small‐Molecule Inhibitors
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DOI: 10.1002/cbic.202000194
Abstract: Modifications of nuclear and cytoplasmic proteins with a single sugar, N‐acetylglucosamine (GlcNAc), play roles in a wide variety of fundamental cellular processes, and aberrant O‐GlcNAc profiles are associated with pathological progression of several chronic diseases.… read more here.
Keywords: glcnac transferase; catalytic mechanism; structural characteristics; transferase structural ... See more keywords