Nanocrystal facet modulation to enhance transferrin binding and cellular delivery
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DOI: 10.1038/s41467-020-14972-z
Abstract: Binding of biomolecules to crystal surfaces is critical for effective biological applications of crystalline nanomaterials. Here, we present the modulation of exposed crystal facets as a feasible approach to enhance specific nanocrystal–biomolecule associations for improving… read more here.
Keywords: modulation; delivery; transferrin binding; facet ... See more keywords
Point Mutations in TbpA Abrogate Human Transferrin Binding in Neisseria gonorrhoeae
Sign Up to like & getrecommendations! Published in 2022 at "Infection and Immunity"
DOI: 10.1128/iai.00414-22
Abstract: TonB-dependent transporters (TDTs) are essential proteins for metal acquisition, an important step in the growth and pathogenesis of many pathogens, including Neisseria gonorrhoeae, the causative agent of gonorrhea. There is currently no available vaccine for… read more here.
Keywords: neisseria gonorrhoeae; transferrin; transferrin binding; human transferrin ... See more keywords
Utility of Hybrid Transferrin Binding Protein Antigens for Protection Against Pathogenic Neisseria Species
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.00247
Abstract: The surface transferrin receptor proteins from Neisseria gonorrhoeae have been recognized as ideal vaccine targets due to their critical role in survival in the human male genitourinary tract. Recombinant forms of the surface lipoprotein component… read more here.
Keywords: protein; tbpa; surface; transferrin binding ... See more keywords