BRCA2 promoter hypermethylation as a biomarker for the leukemic transformation of myeloproliferative neoplasms.
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DOI: 10.2217/epi-2022-0025
Abstract: Aim: To characterize the actionable biomarker for leukemic transformation (LT) of myeloproliferative neoplasms (MPNs) at the DNA damage repair promoter methylation level. Materials & methods: Bioinformatic analysis and experimental validation were performed to identify the… read more here.
Keywords: promoter; biomarker leukemic; transformation myeloproliferative; leukemic transformation ... See more keywords