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Transformation to small cell lung cancer after first-line afatinib treatment

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Published in 2018 at "Respiratory Medicine Case Reports"

DOI: 10.1016/j.rmcr.2018.02.011

Abstract: Acquiring resistance to epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) is inevitable. Transformation to small cell lung cancer (SCLC) is reported as a possible mechanism of this acquired resistance. We describe the case of… read more here.

Keywords: afatinib; transformation; cell lung; transformation small ... See more keywords