Porcine pancreatic ductal epithelial cells transformed with KRASG12D and SV40T are tumorigenic
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DOI: 10.1038/s41598-021-92852-2
Abstract: We describe our initial studies in the development of an orthotopic, genetically defined, large animal model of pancreatic cancer. Primary pancreatic epithelial cells were isolated from pancreatic duct of domestic pigs. A transformed cell line… read more here.
Keywords: epithelial cells; tumorigenic porcine; porcine pancreatic; transformed cell ... See more keywords
Genome-wide identification and analysis of A-to-I RNA editing events in the malignantly transformed cell lines from bronchial epithelial cell line induced by α-particles radiation
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DOI: 10.1371/journal.pone.0213047
Abstract: Adenosine (A) to inosine (I) RNA editing is the most prevalent RNA editing mechanism in humans and plays critical roles in tumorigenesis. However, the effects of radiation on RNA editing were poorly understood, and a… read more here.
Keywords: cell lines; transformed cell; rna editing; malignantly transformed ... See more keywords