Promoting High-Value Practice by Reducing Unnecessary Transfusions With a Patient Blood Management Program
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Internal Medicine"
DOI: 10.1001/jamainternmed.2017.6369
Abstract: Although blood transfusion is a lifesaving therapy for some patients, transfusion has been named 1 of the top 5 overused procedures in US hospitals. As unnecessary transfusions only increase risk and cost without providing benefit,… read more here.
Keywords: patient blood; blood management; transfusion; blood ... See more keywords
Evaluation of the Association of Platelet Count, Mean Platelet Volume, and Platelet Transfusion With Intraventricular Hemorrhage and Death Among Preterm Infants
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.37588
Abstract: Key Points Question What are the associations of platelet transfusion, platelet count (PC), and mean platelet volume (MPV) with intraventricular hemorrhage (IVH) and mortality in preterm infants? Findings In this cohort study of 1221 preterm… read more here.
Keywords: count mean; platelet transfusion; preterm infants; platelet ... See more keywords
Association of Prehospital Transfusion With Mortality in Pediatric Trauma.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA pediatrics"
DOI: 10.1001/jamapediatrics.2023.1291
Abstract: Importance Optimal hemostatic resuscitation in pediatric trauma is not well defined. Objective To assess the association of prehospital blood transfusion (PHT) with outcomes in injured children. Design, Setting, and Participants This retrospective cohort study of… read more here.
Keywords: mortality; cohort; transfusion; pht ... See more keywords
The impact of sex on disease phenotype and prognostic thresholds of anemia in myelodysplastic syndromes
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Hematology"
DOI: 10.1002/ajh.25114
Abstract: To the Editor: Current information on sex-specific genetic (including mutations) and clinical details in myelodysplastic syndromes (MDS) is limited. Similarly, the impact of sex on the use of the conventional 10 g/dl hemoglobin threshold, for… read more here.
Keywords: transfusion; hemoglobin threshold; impact sex; hemoglobin level ... See more keywords
Management of non‐transfusion‐dependent β‐thalassemia (NTDT): The next 5 years
Sign Up to like & getrecommendations! Published in 2020 at "American Journal of Hematology"
DOI: 10.1002/ajh.26055
Abstract: To the Editor: Management of patients with β-thalassemia is undergoing a swift evolution, considering the number of novel agents recently receiving marketing approval or entering clinical development. Although (thankfully) the availability of new treatment options… read more here.
Keywords: ineffective erythropoiesis; thalassemia; management; transfusion ... See more keywords
Form follows function for freeze‐dried platelets
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26460
Abstract: Platelets—essential players in hemostasis—represent major challenges in hematology and transfusion medicine. Demand for platelets remains high in many clinical contexts including hematology-oncology, transplant surgery, cardiac surgery, and trauma medicine. Yet, supply from donors is fragile,… read more here.
Keywords: freeze dried; dried platelets; hematology; platelet ... See more keywords
Transferrin receptor 2 (Tfr2) genetic deletion makes transfusion‐independent a murine model of transfusion‐dependent β‐thalassemia
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26673
Abstract: β‐thalassemia is a genetic disorder caused by mutations in the β‐globin gene, and characterized by anemia, ineffective erythropoiesis and iron overload. Patients affected by the most severe transfusion‐dependent form of the disease (TDT) require lifelong… read more here.
Keywords: transfusion dependent; deletion; iron; transferrin receptor ... See more keywords
Restrictive vs liberal red blood cell transfusion strategies in patients with acute myocardial infarction and anemia: Rationale and design of the REALITY trial
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Cardiology"
DOI: 10.1002/clc.23453
Abstract: Anemia is common in patients with acute myocardial infarction (AMI), and is an independent predictor of mortality. The optimal transfusion strategy in these patients is unclear. read more here.
Keywords: patients acute; myocardial infarction; transfusion; restrictive liberal ... See more keywords
Transcriptomic biomarkers of altered erythropoiesis to detect autologous blood transfusion.
Sign Up to like & getrecommendations! Published in 2018 at "Drug testing and analysis"
DOI: 10.1002/dta.2240
Abstract: Autologous blood transfusion is a powerful means of improving performance and remains one of the most challenging methods to detect. Recent investigations have identified 3 candidate reticulocytes genes whose expression was significantly influenced by blood… read more here.
Keywords: autologous blood; transfusion; transcriptomic biomarkers; biomarkers altered ... See more keywords
Evaluation of the detection of the homologous transfusion of a red blood cell concentrate in vivo for antidoping.
Sign Up to like & getrecommendations! Published in 2023 at "Drug testing and analysis"
DOI: 10.1002/dta.3448
Abstract: Two doping cases of homologous blood transfusion (HBT) during Tokyo 2020 Summer Olympics have shown that more controls are needed. The method of detection using flow cytometry to evaluate the expression of minor blood group… read more here.
Keywords: dna; red blood; detection; analysis ... See more keywords
[The new hemotherapy guideline].
Sign Up to like & getrecommendations! Published in 2018 at "Der Unfallchirurg"
DOI: 10.1007/s00113-018-0489-4
Abstract: The 2017 update of the German guidelines on hemotherapy is highly associated with the drug legislation and guidelines and thus necessitated a new structure of the contents. These guidelines reflect the state of the art for… read more here.
Keywords: hemotherapy; hemotherapy guideline; transfusion; blood ... See more keywords