Differential protein expression of blood platelet components associated with adverse transfusion reactions.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of proteomics"
DOI: 10.1016/j.jprot.2018.12.019
Abstract: Platelets found within platelet components (PCs) intended for transfusion release inflammatory molecules. Despite the implementation of leukoreduction, some of these PCs are occasionally associated with adverse transfusion reactions (ATRs). The aim of this study was… read more here.
Keywords: sda pcs; transfusion reactions; platelet components; transfusion ... See more keywords
Adverse transfusion reactions and what we can do
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Hematology"
DOI: 10.1080/17474086.2022.2112564
Abstract: ABSTRACT Introduction Transfusions of blood and blood components have inherent risks and the ensuing adverse reactions. It is very important to understand the adverse reactions of blood transfusion comprehensively for ensuring the safety of any… read more here.
Keywords: adverse reactions; blood transfusion; transfusion reactions; transfusion ... See more keywords
Application of Standardized Residual Component Culture Criteria for Suspected Septic Transfusion Reactions Would Increase the Component Culturing Rate at a Single Academic Medical Center.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of clinical pathology"
DOI: 10.1093/ajcp/aqac032
Abstract: OBJECTIVES The 2019 SCARED study developed the Biomedical Excellence for Safer Transfusion (BEST) criteria in an effort to standardize the decision to culture residual units in the context of suspected septic transfusion reactions (STRs). The… read more here.
Keywords: culture; application; best criteria; suspected septic ... See more keywords
Mild Allergic Transfusion Reactions: Impact of Associated Clinical Symptoms?
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Clinical Pathology"
DOI: 10.1093/ajcp/aqy150
Abstract: Objectives: Transfusions are often needlessly aborted after occurrence of a mild allergic transfusion reaction (ATR), leading to wastage and reexposure of recipients to additional blood products (with potential alloimmunization). We aimed to determine the symptoms… read more here.
Keywords: allergic transfusion; reactions impact; impact associated; transfusion reactions ... See more keywords
The cause and pathogenesis of hemolytic transfusion reactions in sickle-cell disease.
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Hematology"
DOI: 10.1097/moh.0000000000000546
Abstract: PURPOSE OF REVIEW The current review aims to summarize the epidemiology, cause, pathophysiology, and management of hemolytic transfusion reactions in sickle-cell disease (SCD). RECENT FINDINGS Patients undergoing occasional, isolated transfusions have been shown to have… read more here.
Keywords: hemolytic transfusion; transfusion; reaction; cell ... See more keywords
The epidemiology of bacterial culture–positive and septic transfusion reactions at a large tertiary academic center: 2009 to 2016
Sign Up to like & getrecommendations! Published in 2018 at "Transfusion"
DOI: 10.1111/trf.14789
Abstract: Bacterial contamination and associated septic transfusion reactions (STRs) remain the leading infectious risk to the blood supply. We sought to characterize the risk and clinical presentation of blood culture–positive transfusion reactions (BCPTRs) and STRs at… read more here.
Keywords: culture positive; transfusion; septic transfusion; epidemiology ... See more keywords
Immunoglobulin (Ig)G antibodies against IgE identified by basophil activation test as the putative causative agent of a serious allergic transfusion reaction: potential utility of the test as a new safety measure for allergic transfusion reactions
Sign Up to like & getrecommendations! Published in 2018 at "Transfusion"
DOI: 10.1111/trf.14878
Abstract: In most cases of allergic transfusion reactions (ATRs), the causative agents have not been identified and the mechanisms are largely unknown, with a few exceptions. The basophil activation test (BAT) was recently introduced in the… read more here.
Keywords: allergic transfusion; activation test; basophil activation; transfusion ... See more keywords
Multiple hemolytic transfusion reactions misinterpreted as severe vaso‐occlusive crisis in a patient with sickle cell disease
Sign Up to like & getrecommendations! Published in 2019 at "Transfusion"
DOI: 10.1111/trf.15010
Abstract: Hemolytic transfusion reactions are a rare, yet serious complication of red blood cell (RBC) transfusion. Patients with sickle cell disease (SCD) are at an increased risk for such reactions, because they are prone to make… read more here.
Keywords: hemolytic transfusion; disease; transfusion; cell ... See more keywords
Prevention of hemolytic transfusion reactions with intravenous immunoglobulin prophylaxis in U– patients with anti‐U
Sign Up to like & getrecommendations! Published in 2019 at "Transfusion"
DOI: 10.1111/trf.15230
Abstract: The U– phenotype is extremely rare and is found predominantly in black African populations at a frequency of between 0.2 and 1.7%. In European populations, U– units are therefore rare, with limited availability in the… read more here.
Keywords: intravenous immunoglobulin; hemolytic transfusion; transfusion; reactions intravenous ... See more keywords
Hypersensitivity transfusion reactions to platelet concentrate: a retrospective analysis of the French hemovigilance network
Sign Up to like & getrecommendations! Published in 2019 at "Transfusion"
DOI: 10.1111/trf.15275
Abstract: Among labile blood products, platelet concentrates (PCs) are the leading cause of hypersensitivity transfusion reactions (HTRs). These reactions often lead to interruption of PC transfusion and can result in a prolonged transfusion process leading to… read more here.
Keywords: transfusion; french hemovigilance; transfusion reactions; hypersensitivity transfusion ... See more keywords
The BEST criteria improve sensitivity for detecting positive cultures in residual blood components cultured in suspected septic transfusion reactions
Sign Up to like & getrecommendations! Published in 2019 at "Transfusion"
DOI: 10.1111/trf.15317
Abstract: Culturing residual blood components after suspected septic transfusion reactions guides management of patients and cocomponents. Current practice, accuracy of provider vital sign assessment, and performance of the AABB culture criteria are unknown. A multicenter international… read more here.
Keywords: residual blood; blood components; transfusion; suspected septic ... See more keywords