Articles with "transgene levels" as a keyword



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Abstract CT237: Evaluation of in vivo chimeric antigen receptor (CAR) transgene levels in patients (pts) treated with tisagenlecleucel

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Published in 2019 at "Clinical Trials"

DOI: 10.1158/1538-7445.am2019-ct237

Abstract: Background: Following infusion of tisagenlecleucel, quantitative polymerase chain reaction (qPCR) can be used to measure in vivo kinetics of CAR transgene. The utility of qPCR to inform individual pt treatment decisions and measure functional persistence… read more here.

Keywords: evaluation vivo; transgene levels; car transgene; transgene ... See more keywords